ArticleLipids in health and disease2016
Dyslipidemia in rural areas of North China: prevalence, characteristics, and predictive value.
Article in Lipids in health and disease, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.
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Who cites it
18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 33 citations in OpenAlex.
- The association between rapid growth and lipid profile: a systematic review and meta-analysis.Frontiers in endocrinology · 2024Pooled it
- Association between serum uric acid levels and dyslipidemia in Chinese adults: A cross-sectional study and further meta-analysis.Medicine · 2020Pooled it
- Gut microbial alterations and functional shifts in patients with hypertriglyceridemia: insights from a northwestern Chinese metagenomic study.International microbiology : the official journal of the Spanish Society for Microbiology · 2026Article
- The Prevalence of Abnormal Glucose Metabolism and Its Correlates in the Zhuang Nationality, Nanning, Guangxi Province.Journal of clinical laboratory analysis · 2025Article
- The Association Between Serum Uric Acid Levels and the 10-Year Prospective Risk of Dyslipidemia: A Cohort Study From Healthy Heart Project (YHHP).Health science reports · 2025Article
- Automated process assessment of primary healthcare for hyperlipidemia: preliminary findings and implications form Anhui, China.Lipids in health and disease · 2025Article
- Persistent dyslipidemia increases the longitudinal changes in telomere length.Lipids in health and disease · 2023Article
- Association between dyslipidaemia and the risk of hyperuricaemia: a six-year longitudinal cohort study of elderly individuals in China.Annals of medicine · 2022Article
- Efficacy and safety of tai chi for hyperlipidaemia: a protocol for systematic review and meta-analysis.BMJ open · 2022Article
- Associations of gut microbiota with dyslipidemia based on sex differences in subjects from Northwestern China.World journal of gastroenterology · 2022Article
- The Relationship Between Sleep Duration and Blood Lipids Among Chinese Middle-Aged and Older Adults: Cross-Lagged Path Analysis From CHARLS.Frontiers in public health · 2022Article
- Prevalence and related factors of dyslipidemia among urban adults aged 35 to 79 years in Southwestern China.Scientific reports · 2021Article
- Prevalence and risk factors for dyslipidemia among adults in rural and urban China: findings from the China National Stroke Screening and prevention project (CNSSPP).BMC public health · 2019Article
- Prevalence of hypertension and hypertension control rates among elderly adults during the cold season in rural Northeast China: a cross-sectional study.Journal of rural medicine : JRM · 2018Article
- A Study on the Factors Influencing Triglyceride Levels among Adults in Northeast China.Scientific reports · 2018Article
- Prevalence of hyperlipidemia in Shanxi Province, China and application of Bayesian networks to analyse its related factors.Scientific reports · 2018Article
- Genetic and microbiome influence on lipid metabolism and dyslipidemia.Physiological genomics · 2018Review
- Prevalence, patterns and predictors of dyslipidaemia in Nigeria: a report from the REMAH study.Cardiovascular journal of AfricaArticle
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Authors and funding
11 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe prevalence of cardiovascular disease has been increasing worldwide. As a common pathogenic risk factor, dyslipidemia played a great role in the incidence and progress of these diseases. We investigated to achieve accurate and up-to-date information on the prevalence of dyslipidemia and its associations with other lipid-related diseases in rural North China.
methodsUsing a complex, multistage, probability sampling design, we conducted a large-scale cross-sectional study of 8528 rural participants aged over 18 years in Shandong Province. Prevalence and characteristics of dyslipidemia were demonstrated. The odds ratios between dyslipidemia types and lipid-related diseases were further analyzed by logistic regression.
resultsAmong the overall population, 45.8 % suffered from dyslipidemia. The prevalence of lipid abnormality (including high and very high levels) was 18.6, 12.7, 9.8 and 12.7 % for total cholesterol (TC), high-density lipoprotein (HDL), and low-density lipoprotein (LDL) cholesterol and triglycerides (TG), respectively. Among all participants with dyslipidemia, 23.9 % were aware, only 11.5 % were treated, 10.0 % were controlled. For subjects with dyslipidemia, the risk for non-alcoholic fatty liver disease (NAFLD) was highest with a 3.3-fold over that of non-dyslipidmia (OR = 3.30, P < 0.001); followed by hyperuricemia and diabetes mellitus (DM), while with 2-fold increase (OR = 1.99, P < 0.001; OR = 1.92, P < 0.001); with only 1.5-fold risk for atherosclerosis (AS) (OR = 1.47, P < 0.001). The presence of high cholesterol was mainly associated with AS, while abnormal TG was correlated with NAFLD and DM.
conclusionsDyslipidemia has become a serious public health issue in rural North China. The rapid increase of high TC and incremental risk of high TG may contribute to the epidemic of AS, NAFLD and DM. It is imperative to develop individualized prevention and treatment guidelines according to dyslipidemia phenotypes.
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