Evidence map›Paper›PMID 27619010›Full record

ArticleAddictive behaviors2017

PTSD, alcohol dependence, and conduct problems: Distinct pathways via lability and disinhibition.

Jeffrey S Simons, Raluca M Simons, Carol O'Brien, Scott F Stoltenberg, Jessica A Keith, Jaime A Hudson

Abstract read
In one paragraph

Article in Addictive behaviors, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Trial
  2. Article
  3. Review
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. A Critical Review of Behavioral and Emotional Disinhibition.The Journal of nervous and mental disease · 2020
    Review
  12. Nexus of despair: A network analysis of suicidal ideation among veterans.Archives of suicide research : official journal of the International Academy for Suicide Research · 2020
    Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jeffrey S SimonsThe University of South Dakota, Vermillion, SD, United States; Sioux Falls VA Medical Center, Sioux Falls, SD, United States.
Raluca M SimonsThe University of South Dakota, Vermillion, SD, United States; Sioux Falls VA Medical Center, Sioux Falls, SD, United States.
Carol O'BrienBay Pines VA Health Care System, Bay Pines, FL, United States.
Scott F StoltenbergThe University of Nebraska - Lincoln, Lincoln, NE, United States.
Jessica A KeithBay Pines VA Health Care System, Bay Pines, FL, United States.
Jaime A HudsonSioux Falls VA Medical Center, Sioux Falls, SD, United States.

Funding

Traumatic Stress and Alcohol Problems: Between- and Within- Person AssociationsR01AA020519 · NIAAA · UNIVERSITY OF SOUTH DAKOTA · PI SIMONS, JEFFREY S · 2012 to 2015
$1.6M
NIAAA NIH HHS R01 AA020519
6 · The paper itself

Abstract

This study tested the role of affect lability and disinhibition in mediating associations between PTSD symptoms and two forms of alcohol-related problems, dependence syndrome symptoms (e.g., impaired control over consumption) and conduct problems (e.g., assault, risk behaviors). Genotype at the serotonin transporter linked polymorphic region (5-HTTLPR) was hypothesized to moderate associations between traumatic stress and PTSD symptoms. In addition, the study tested whether childhood traumatic stress moderated associations between combat trauma and PTSD symptoms. Participants were 270 OIF/OEF/OND veterans. The hypothesized model was largely supported. Participants with the low expression alleles of 5-HTTLPR (S or L

Indexed as

AdultAlcoholismChildChild AbuseConduct DisorderFemaleHumansMaleMiddle AgedRisk FactorsSerotonin Plasma Membrane Transport ProteinsStress Disorders, Post-TraumaticUnited StatesVeteransYoung AdultSerotonin Plasma Membrane Transport ProteinsSLC6A4 protein, humanAffect dysregulationAlcohol use disorderPTSDrs25531SLC6A4

Identifiers

PMID27619010
PMCPMC5143199

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.