ArticleScientific reports2016
De novo sequencing, assembly and analysis of eight different transcriptomes from the Malayan pangolin.
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 25 citations in OpenAlex.
- Transcriptomic Analysis Reveals Multilayer Regulation Underlying Development and Pregnancy in the Malayan Pangolin.Animal genetics · 2026Article
- Metagenomics and metabolomics analyses of the mechanism of non-expression of natural mating behavior in captive male Malayan pangolins (Frontiers in microbiology · 2026Article
- Transcriptomic Data Reveal Divergent Paths of Chitinase Evolution Underlying Dietary Convergence in Anteaters and Pangolins.Genome biology and evolution · 2025Article
- New horizons in the reproductive biology of Chinese pangolin (Manis pentadactyla) using the gonadal hormonal profile.Scientific reports · 2023Article
- Hologenomic insights into mammalian adaptations to myrmecophagy.National science review · 2023Article
- Research-ready data: the C-Surv data model.European journal of epidemiology · 2023Article
- Article
- Genomic consequences of population decline in critically endangered pangolins and their demographic histories.National science review · 2020Article
- Acidic mammalian chitinase gene is highly expressed in the special oxyntic glands ofFEBS open bio · 2018Article
- Transcriptomic analysis identifies genes and pathways related to myrmecophagy in the Malayan pangolin (PeerJ · 2017Article
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Authors and funding
14 authors at 6 institutions in 4 countries.
Funding
Abstract
Pangolins are scale-covered mammals, containing eight endangered species. Maintaining pangolins in captivity is a significant challenge, in part because little is known about their genetics. Here we provide the first large-scale sequencing of the critically endangered Manis javanica transcriptomes from eight different organs using Illumina HiSeq technology, yielding ~75 Giga bases and 89,754 unigenes. We found some unigenes involved in the insect hormone biosynthesis pathway and also 747 lipids metabolism-related unigenes that may be insightful to understand the lipid metabolism system in pangolins. Comparative analysis between M. javanica and other mammals revealed many pangolin-specific genes significantly over-represented in stress-related processes, cell proliferation and external stimulus, probably reflecting the traits and adaptations of the analyzed pregnant female M. javanica. Our study provides an invaluable resource for future functional works that may be highly relevant for the conservation of pangolins.
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