ArticleJournal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance2016
Aortic stiffening and its impact on left atrial volumes and function in patients after successful coarctation repair: a multiparametric cardiovascular magnetic resonance study.
Article in Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 38 citations in OpenAlex.
- Risk Factors for Reintervention Following Treatment for Aortic Coarctation With or Without Aortic Arch Hypoplasia in Sweden: From Isolated Coarctation to Complex Bi- and Univentricular Congenital Heart Disease.Journal of the American Heart Association · 2025Article
- Hemodynamic interplay of ventricular, atrial and aortic function in patients after arterial switch operation: insights from cardiac MRI.Cardiovascular diagnosis and therapy · 2025Article
- Relationship between left atrial myopathy and atrial fibrillation in adults with coarctation of aorta.American heart journal plus : cardiology research and practice · 2023Article
- Editorial: Aortopathy in congenital heart disease.Frontiers in cardiovascular medicine · 2023Article
- Vascular aging in adult congenital heart disease-a narrative review.Cardiovascular diagnosis and therapy · 2022Review
- Preclinical Aortic Atherosclerosis in Adolescents With Chronic Disease.Journal of the American Heart Association · 2022Article
- Common carotid artery characteristics in patients with repaired aortic coarctation compared to other cardiovascular risk factors.International journal of cardiology. Congenital heart disease · 2022Article
- Impaired left atrial function in adults and adolescents with corrected aortic coarctation.Pediatric cardiology · 2021Article
- Increased prevalence of left ventricular diastolic dysfunction in adults with repaired coarctation of aorta.International journal of cardiology. Heart & vasculature · 2020Article
- Observational
- Is Carotid Intima-Media Thickness Increased in Adults With Congenital Heart Disease?Journal of the American Heart Association · 2020Article
- Aortic elasticity after aortic coarctation relief: comparison of surgical and interventional therapy by cardiovascular magnetic resonance imaging.BMC cardiovascular disorders · 2019Article
- The effects of age at correction of aortic coarctation and recurrent obstruction on adolescent patients: MRI evaluation of wall shear stress and pulse wave velocity.European radiology experimental · 2019Article
- Journal of Cardiovascular Magnetic Resonance 2017.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2018Review
- Impaired aortic distensibility and elevated central blood pressure in Turner Syndrome: a cardiovascular magnetic resonance study.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2018Article
- Impact of different coarctation therapies on aortic stiffness: phase-contrast MRI study.The international journal of cardiovascular imaging · 2018Article
- Are aortic coarctation and rheumatoid arthritis different models of aortic stiffness? Data from an echocardiographic study.Cardiovascular ultrasound · 2018Article
- Stroke in Adults With Coarctation of the Aorta: A National Population-Based Study.Journal of the American Heart Association · 2018Article
- Preserved Cardiac Blood Supply-Workload Balance in Pediatric Patients After Aortic Arch Repair.Pediatric cardiology · 2018Article
- Review of Journal of Cardiovascular Magnetic Resonance (JCMR) 2015-2016 and transition of the JCMR office to Boston.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2017Review
Corrections and comments
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Authors and funding
15 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe increased cardiovascular morbidity of adults with late repair of aortic coarctation (CoA) has been well documented. In contrast, successful CoA repair in early childhood has a generally good prognosis, though adverse vascular and ventricular characteristics may be abnormal, which could increase long-term risk. This study sought to perform a comprehensive analysis of aortic elasticity and left ventricular (LV) function in patients with aortic coarctation (CoA) using cardiovascular magnetic resonance (CMR). In a subgroup of patients, we assessed structure and function of the common carotid arteries to probe for signs of systemic vascular remodeling.
methodsFifty-one patients (median age 17.3 years), 13.9 ± 7.5 years after CoA repair, and 54 controls (median age 19.8 years) underwent CMR. We determined distensibility and pulse wave velocity (PWV) at different aortic locations. In a subgroup, common carotid artery distensibility, PWV, wall thickness and wall area were measured. LV ejection fraction (EF), volumes, and mass were measured from short axis views. Left atrial (LA) volumes and functional parameters (LAEFPassive, LAEFContractile, LAEFReservoir) were assessed from axial cine images.
resultsIn patients distensibility of the whole thoracic aorta was reduced (p < 0.05) while PWV was only significantly higher in the aortic arch (p < 0.01). Distensibility of the descending aorta at the level of the pulmonary arteries and PWV in the descending aorta, both correlated negatively with age at CoA repair. LA volume before atrial contraction and minimal LA volume were higher in patients (p < 0.05). LAEFPassive and LAEFReservoir were reduced (p < 0.05), and LAEFReservoir correlated negatively with aortic arch PWV (p < 0.05). LVEF, volumes and mass were not different from controls. Carotid wall thickness and PWV were higher in patients compared to controls (p < 0.05).
conclusionsPatients after CoA repair have impaired bioelastic properties of the thoracic aorta with impact on LV diastolic function. Reduced descending aortic elasticity is associated with older age at time of CoA repair. The remodeling of the common carotid artery in our sub-study suggests systemic vessel wall changes.
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