ArticleJournal of clinical medicine2016
Adherence to Glaucoma Medications Over 12 Months in Two US Community Pharmacy Chains.
Article in Journal of clinical medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 35 citations in OpenAlex.
- Direct selective laser trabeculoplasty in open angle glaucoma study design: a multicentre, randomised, controlled, investigator-masked trial (GLAUrious).The British journal of ophthalmology · 2023Trial
- The Association between Medication Adherence and Visual Field Progression in the Collaborative Initial Glaucoma Treatment Study.Ophthalmology · 2020Trial
- The Effect of an Educational Intervention on Adherence to Intraocular Pressure-Lowering Medications in a Large Cohort of Older Adults with Glaucoma.Journal of managed care & specialty pharmacy · 2018Trial
- Clinical and Histopathological Evaluation of Maximal and Supramaximal Energy Direct Selective Laser Trabeculoplasty (DSLT): A Rabbit Model Safety Study.Lasers in surgery and medicine · 2026Article
- Melanin-Binding-Based Discovery of Topically Instilled Carbonic Anhydrase Inhibitors for Targeted Delivery and Prolonged Action in the Eye.Molecular pharmaceutics · 2025Article
- Glaucoma medication non-adherence rate and associated barriers among glaucoma patients in Hawassa, Ethiopia.BMC ophthalmology · 2024Article
- Predictors and long-term patterns of medication adherence to glaucoma treatment in Denmark-an observational registry study of 30 100 Danish patients with glaucoma.BMJ open ophthalmology · 2024Article
- Adherence and Persistence to Medical Therapy in Glaucoma: An Overview.Ophthalmology and therapy · 2023Review
- Perspectives on Adherence to Glaucoma Medical Therapy in Brazilian Patients.Pharmaceutical medicine · 2023Article
- Heritable Risk and Protective Genetic Components of Glaucoma Medication Non-Adherence.International journal of molecular sciences · 2023Article
- Intraocular nano-microscale drug delivery systems for glaucoma treatment: design strategies and recent progress.Journal of nanobiotechnology · 2023Review
- Transgene expression of Stanniocalcin-1 provides sustained intraocular pressure reduction by increasing outflow facility.PloS one · 2022Article
- Artificial Intelligence, Heuristic Biases, and the Optimization of Health Outcomes: Cautionary Optimism.Journal of clinical medicine · 2021Article
- Efficacy of Selective Laser Trabeculoplasty after iStent Implantation in Primary Open-Angle Glaucoma.Journal of personalized medicine · 2021Article
- Extraocular, periocular, and intraocular routes for sustained drug delivery for glaucoma.Progress in retinal and eye research · 2021Review
- Ab interno trabeculotomy combined with cataract extraction in eyes with primary open-angle glaucoma.The Journal of international medical research · 2020Article
- Non-contact direct selective laser trabeculoplasty: light propagation analysis.Biomedical optics express · 2020Article
- Ab interno canaloplasty combined with trabecular bypass stenting in eyes with primary open-angle glaucoma.Clinical ophthalmology (Auckland, N.Z.) · 2019Article
- Proportion of Japanese outpatients filling prescriptions for long-term medication regimens.Patient preference and adherence · 2019Article
- Article
Corrections and comments
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Authors and funding
11 authors at 1 institution in 1 country.
Funding
Abstract
unlabelledThis study determined the degree of adherence to medications for glaucoma among patients refilling prescriptions in community pharmacies.
methodsData abstracted from the dispensing records for 3615 adult patients (18 years or older, predominantly over 45) receiving glaucoma medications from two retail pharmacy chains (64 stores in total) were analyzed. From a 24-month historic data capture period, the 12-month levels of adherence were determined using standard metrics, the proportion of days covered (PDC) and the medication possession ratio (MPR). The overall 12-month mean PDC was only 57%, and the mean MPR was 71%. Using a criterion by which 80% coverage was considered satisfactory adherence, only 30% had satisfactory overall 12-month PDC coverage, and only 37% had satisfactory overall 12-month MPR coverage. Refill adherence increased with age and was highest in the 65-and-older age group (p < 0.001). Differential adherence was found across medication classes, with the highest satisfactory coverage seen for those taking alpha2-adrenergic agonists (PDC = 36.0%; MPR = 47.6%) down to those taking direct cholinergic agonists (PDC = 25.0%; MPR = 31.2%) and combination products (PDC = 22.7%; MPR = 31.0%). Adherence to glaucoma medications in the community setting, as measured by pharmacy refill data, is very poor and represents a critical target for intervention. Community pharmacists are well positioned to monitor and reinforce adherence in this population.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.