ReviewInternational journal of molecular sciences2016
Advances and Future Applications of Augmented Peripheral Nerve Regeneration.
Review in International journal of molecular sciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
47 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Mesenchymal Stem Cell Treatment Perspectives in Peripheral Nerve Regeneration: Systematic Review.International journal of molecular sciences · 2021Pooled it
- Low-intensity pulsed ultrasound for regenerating peripheral nerves: potential for penile nerve.Asian journal of andrologyPooled it
- SUN11602 Accelerates Early Peripheral Nerve Regeneration in an Experimental Median Nerve Transection Model.Journal of cellular and molecular medicine · 2026Article
- Improved Motor Neuron Preservation and Axonal Recovery Following Experimental Sciatic Nerve Repair With Heterologous Fibrin Biopolymer.The European journal of neuroscience · 2026Article
- LARP7 enhances the potential of dental pulp stem cells to promote peripheral nerve repair.Stem cells (Dayton, Ohio) · 2026Article
- Where Do We Stand for Nerve Regeneration and Functional Recovery After Vascularized Composite Allotransplantation?Microsurgery · 2026Review
- PRP-related biomaterials enhance bone and nerve repair.Materials today. Bio · 2026Review
- Biomaterial and Hydrogel Strategies for Regenerative Microenvironment Reconstruction in Peripheral Nerve Conduits.Gels (Basel, Switzerland) · 2025Review
- Aging and Corneal Nerve Health: Mechanisms of Degeneration and Emerging Therapies for the Cornea.Cells · 2025Review
- Volumetric Additive Manufacturing for Cell Printing: Bridging Industry Adaptation and Regulatory Frontiers.ACS biomaterials science & engineering · 2025Review
- Heterologous fibrin biopolymer as an emerging approach to peripheral nerve repair: a scoping review.The journal of venomous animals and toxins including tropical diseases · 2024Article
- The Porous Structure of Peripheral Nerve Guidance Conduits: Features, Fabrication, and Implications for Peripheral Nerve Regeneration.International journal of molecular sciences · 2023Review
- The significance of M1 macrophage should be highlighted in peripheral nerve regeneration.Histology and histopathology · 2023Review
- Stem Cells and Tissue Engineering-Based Therapeutic Interventions: Promising Strategies to Improve Peripheral Nerve Regeneration.Cellular and molecular neurobiology · 2023Review
- Laser-Structured Si and PLGA Inhibit the Neuro2a Differentiation in Mono- and Co-Culture with Glia.Tissue engineering and regenerative medicine · 2023Article
- Neural grafts containing exosomes derived from Schwann cell-like cells promote peripheral nerve regeneration in rats.Burns & trauma · 2023Article
- Molecular Mechanism of Action of Low-Intensity Extracorporeal Shockwave Therapy for Regenerating Penile and Peripheral Nerves.Turkish journal of urology · 2022Article
- Preparation of Polyvinylidene Fluoride-Gold Nanoparticles Electrospinning Nanofiber Membranes.Bioengineering (Basel, Switzerland) · 2022Article
- Typical and atypical properties of peripheral nerve allografts enable novel strategies to repair segmental-loss injuries.Journal of neuroinflammation · 2022Review
- Gastrodin promotes the regeneration of peripheral nerves by regulating miR-497/BDNF axis.BMC complementary medicine and therapies · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Peripheral nerve injuries remain a significant source of long lasting morbidity, disability, and economic costs. Much research continues to be performed in areas related to improving the surgical outcomes of peripheral nerve repair. In this review, the physiology of peripheral nerve regeneration and the multitude of efforts to improve surgical outcomes are discussed. Improvements in tissue engineering that have allowed for the use of synthetic conduits seeded with neurotrophic factors are highlighted. Selected pre-clinical and available clinical data using cell based methods such as Schwann cell, undifferentiated, and differentiated stem cell transplantation to guide and enhance peripheral nerve regeneration are presented. The limitations that still exist in the utility of neurotrophic factors and cell-based therapies are outlined. Strategies that are most promising for translation into the clinical arena are suggested.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.