Evidence map›Paper›PMID 27617985›Full record

SynthesisMolecules (Basel, Switzerland)2016

A Systematic Review on the Implication of Minerals in the Onset, Severity and Treatment of Periodontal Disease.

Alfonso Varela-López, Francesca Giampieri, Pedro Bullón, Maurizio Battino, José L Quiles

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in Molecules (Basel, Switzerland), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Dietary Factors Affecting the Prevalence and Impact of Periodontal Disease.Clinical, cosmetic and investigational dentistry · 2021
    Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Alfonso Varela-LópezDepartment of Physiology, Institute of Nutrition and Food Technology "Jose Mataix", University of Granada, Biomedical Research Center, Avda. Conocimiento s.n., 18100 Armilla, Granada, Spain. alvarela@ugr.es.
Francesca GiampieriDipartimento di Scienze Cliniche Specialistiche ed Odontostomatologiche (DISCO)-Sez. Biochimica, Facoltà di Medicina, Università Politecnica delle Marche, 60131 Ancona, Italy. f.giampieri@univpm.it.
Pedro BullónDepartment of Stomalogy, Dental School, University of Sevilla, C/Avicena s.n., 41009 Sevilla, Andalusia, Spain. pbullon@us.es.
Maurizio BattinoDipartimento di Scienze Cliniche Specialistiche ed Odontostomatologiche (DISCO)-Sez. Biochimica, Facoltà di Medicina, Università Politecnica delle Marche, 60131 Ancona, Italy. m.a.battino@univpm.it.
José L QuilesDepartment of Physiology, Institute of Nutrition and Food Technology "Jose Mataix", University of Granada, Biomedical Research Center, Avda. Conocimiento s.n., 18100 Armilla, Granada, Spain. jlquiles@ugr.es.
Marche Polytechnic University · ITUniversidad de Granada · ESUniversidad de Sevilla · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Periodontal disease is an inflammatory disease with high prevalence in adults that leads to destruction of the teeth-supporting tissues. Periodontal therapy has been traditionally directed at reduction of the bacterial load to a level that encourages health-promoting bacteria and maintenance of oral-hygiene. The role of nutrition in different chronic inflammatory diseases has been the subject of an increasing body of research in the last decades. In this sense, there has been an important increase in the volume of research on role of nutrition in periodontitis since the diet has known effects on the immune system and inflammatory cascades. Minerals play a key role in all these processes due to the multiple pathways where they participate. To clarify the role of the different minerals in the establishment, progression and/or treatment of this pathology, a systemically review of published literature cited in PubMed until May 2016 was conducted, which included research on the relationship of these elements with the onset and progression of periodontal disease. Among all the minerals, calcium dietary intake seems important to maintain alveolar bone. Likewise, dietary proportions of minerals that may influence its metabolism also can be relevant. Lastly, some observations suggest that all those minerals with roles in immune and/or antioxidant systems should be considered in future research.

Indexed as

Alveolar ProcessPeriodontal DiseasesAdultChronic DiseaseHumansInflammationMineralsOral HealthMineralscalciumdietmineralnutritionoral healthperiodontitis

Identifiers

PMID27617985
PMCPMC6273540
OpenAlexW2510150595

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.