ArticleGerontology & geriatric medicine
The Comorbid Influence of High Depressive Symptoms and Diabetes on Mortality and Disability in Mexican Americans Aged 75 and Above.
Article in Gerontology & geriatric medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 18 citations in OpenAlex.
- Multimorbidity between Type 2 Diabetes and Depressive Symptoms in Mexico: Prevalence and Associated Factors From the Nationally Representative ENSANUT 2022 Survey.Journal of diabetes · 2026Article
- Liver disease, heart failure, and 13-year mortality among Mexican American older adults: Nativity differences.Annals of epidemiology · 2024Article
- [Cognition and depression in older people with diabetes].Der Nervenarzt · 2024Review
- Caloric Restriction Mimetic 2-Deoxyglucose Reduces Inflammatory Signaling in Human Astrocytes: Implications for Therapeutic Strategies Targeting Neurodegenerative Diseases.Brain sciences · 2022Article
- Mental Health Attribution for Mexican-Origin Latinx and Non-Latinx Older Adults: A Latent Class Analysis.Innovation in aging · 2020Article
- Alterations in brain TREM2 and Amyloid-β levels are associated with neurocognitive impairment in HIV-infected persons on antiretroviral therapy.Journal of neurochemistry · 2018Article
- Aging and Disability Among Hispanics in the United States: Current Knowledge and Future Directions.Innovation in aging · 2017Article
- Influence of Type II Diabetes and High Depressive Symptoms on the Likelihood for Developing Activities of Daily Living (ADL) Disability and Mortality in Older Puerto Ricans.Journal of aging and health · 2017Article
- Haplotype-based interaction of the PPARGC1A and UCP1 genes is associated with impaired fasting glucose or type 2 diabetes mellitus.Medicine · 2017Observational
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
objectiveTo examine the individual and combined effects of depression and diabetes on mortality and disability over 6 years among Mexican Americans aged ≥75.
methodThe final sample included 1,785 participants from the Hispanic Established Population for the Epidemiological Study of the Elderly. Cox proportional hazards regression models were used to estimate the hazard ratios for incidence for mortality and disability according to diabetes and depressive symptoms.
resultsDiabetics were more likely to become activities of daily living (ADL) disabled Hazard Ratio (HR) = 1.44, 95% confidence interval [CI] = [1.18, 1.77]) and deceased (HR = 1.47, 95% CI = [1.24, 1.74]) compared with non-diabetics. Diabetics reporting high depressive symptomatology were more than two times as likely to become ADL disabled and deceased compared with diabetics not reporting high depressive symptoms. Participants with high depressive symptoms and taking insulin alone or both oral medications and insulin were at the greatest risk of disability (HR = 3.83, 95% CI = [1.66, 8.81]).
conclusionDiabetes increases the risk of disability and mortality, especially among Mexican Americans with high depressive symptoms or who are taking insulin alone or both oral medications and insulin. Interventions that are able to reduce the prevalence of depression and diabetes are needed to limit the future burden of disability and mortality in this population.
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