Evidence map›Paper›PMID 27617233›Full record

ReviewFrontiers in cellular and infection microbiology2016

Modulation of the Inflammasome Signaling Pathway by Enteropathogenic and Enterohemorrhagic Escherichia coli.

Hilo Yen, Masaki Karino, Toru Tobe

Abstract readReview
In one paragraph

Review in Frontiers in cellular and infection microbiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Pathophysiology of enteropathogenicJournal of veterinary science · 2022
    Review
  6. Advances in cell death mechanisms involved in viral myocarditis.Frontiers in cardiovascular medicine · 2022
    Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Hilo YenDepartment of Biomedical Informatics, Graduate School of Medicine, Osaka University Osaka, Japan.
Masaki KarinoDepartment of Biomedical Informatics, Graduate School of Medicine, Osaka University Osaka, Japan.
Toru TobeDepartment of Biomedical Informatics, Graduate School of Medicine, Osaka University Osaka, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Innate immunity is an essential component in the protection of a host against pathogens. Enteropathogenic and enterohemorrhagic Escherichia coli (EPEC and EHEC, respectively) are known to modulate the innate immune responses of infected cells. The interference is dependent on their type III secretion system (T3SS) and T3SS-dependent effector proteins. Furthermore, these cytosolically injected effectors have been demonstrated to engage multiple immune signaling pathways, including the IFN/STAT, MAPK, NF-κB, and inflammasome pathways. In this review, recent work describing the interaction between EPEC/EHEC and the inflammasome pathway will be discussed.

Indexed as

Host-Pathogen InteractionsImmune EvasionSignal TransductionAnimalsEnterohemorrhagic Escherichia coliEnteropathogenic Escherichia coliEscherichia coli ProteinsHumansInflammasomesType III Secretion SystemsVirulence FactorsEscherichia coli ProteinsInflammasomesType III Secretion SystemsVirulence Factorseffectorsenteropathogenic Escherichia colienterophenorrhagic Escherichia coliinflammasometype 3 secretion system

Identifiers

PMID27617233
PMCPMC4999430

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.