Evidence map›Paper›PMID 27617098›Full record

ArticleNew microbes and new infections2016

Whole genome sequencing of emerging multidrug resistant Candida auris isolates in India demonstrates low genetic variation.

C Sharma, N Kumar, R Pandey, J F Meis, A Chowdhary

Open access · goldAbstract read
In one paragraph

Article in New microbes and new infections, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 114 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
114citing papers in PubMed, 1 pooled it
18.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

114 citing papers in PubMed, 1 synthesis or guideline pooled it, 199 citations in OpenAlex.

  1. Pooled it
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  12. Epidemiological Trends and Antimicrobial Resistance ofInfection and drug resistance · 2025
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  13. The multidrug-resistantCurrent research in microbial sciences · 2025
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  14. First report ofEmerging microbes & infections · 2024
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  15. Complete genome assembly ofMicrobiology resource announcements · 2024
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  16. Recent increase inAntimicrobial agents and chemotherapy · 2024
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  18. Emergence of the novel sixthMicrobiology spectrum · 2024
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54 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 3 countries.

C SharmaDepartment of Medical Mycology, Vallabhbhai Patel Chest Institute, University of Delhi, Delhi, India.
N KumarWellcome Trust Sanger Institute, Hinxton, UK.
R PandeyCSIR Ayurgenomics Unit-TRISUTRA, Council of Scientific & Industrial Research-Institute of Genomics and Integrative Biology (CSIR-IGIB), New Delhi, India.
J F MeisDepartment of Medical Microbiology and Infectious Diseases, Canisius-Wilhelmina Hospital, Nijmegen, The Netherlands; Department of Medical Microbiology, Radboud UMC, Nijmegen, The Netherlands.
A ChowdharyDepartment of Medical Mycology, Vallabhbhai Patel Chest Institute, University of Delhi, Delhi, India.
University of Delhi · INInstitute of Genomics and Integrative Biology · INRadboud University Nijmegen · NLWellcome Sanger Institute · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Candida auris is an emerging multidrug resistant yeast that causes nosocomial fungaemia and deep-seated infections. Notably, the emergence of this yeast is alarming as it exhibits resistance to azoles, amphotericin B and caspofungin, which may lead to clinical failure in patients. The multigene phylogeny and amplified fragment length polymorphism typing methods report the C. auris population as clonal. Here, using whole genome sequencing analysis, we decipher for the first time that C. auris strains from four Indian hospitals were highly related, suggesting clonal transmission. Further, all C. auris isolates originated from cases of fungaemia and were resistant to fluconazole (MIC >64 mg/L).

Indexed as

Candida aurisIndiamultidrug resistantoutbreakwhole genome sequencing

Identifiers

PMID27617098
PMCPMC5006800
OpenAlexW2473558636

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.