ArticleArrhythmia & electrophysiology review2016
The Significance of Shocks in Implantable Cardioverter Defibrillator Recipients.
Article in Arrhythmia & electrophysiology review, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.
- Impact of carvedilol versus metoprolol on ventricular arrhythmia burden and ICD therapies: a systematic review and meta-analysis.European journal of clinical pharmacology · 2026Pooled it
- Cost-effectiveness of a novel antitachycardia pacing algorithm for the termination of ventricular tachyarrhythmias in the United States.Heart rhythm O2 · 2026Article
- Patients' Perspectives on Applications of AI and Personalized Medicine in Life-Threatening Heart Disease: European Cross-Sectional Patient Questionnaire Study.Journal of medical Internet research · 2026Article
- Visualization of the thoracic sympathetic chain in MLS embalmed body donors: a feasibility study and surgical perspective.Journal of thoracic disease · 2026Article
- Observational
- Incidence of Rapid Rate Non-Sustained and Sustained Ventricular Tachycardia in Implantable Cardioverter-Defibrillator Recipients and Its Correlation With Heart Failure Guideline-Directed Medical Therapy Compliance.Journal of arrhythmia · 2025Article
- Clinical outcomes after ventricular tachycardia ablation with or without induction.Heart rhythm O2 · 2025Article
- The impact of shock therapy on depression development and remote prognosis in cardiac resynchronization therapy recipients.Cardiology journal · 2025Observational
- Subcutaneous Implantable Cardioverter Defibrillator: A Contemporary Overview.Life (Basel, Switzerland) · 2023Review
- Posttraumatic Stress Disorder as a Consequence of Acute Cardiovascular Disease.Current cardiology reports · 2023Review
- The subcutaneous implantable cardioverter-defibrillator should be considered for all patients with an implantable cardioverter-defibrillator indication.Heart rhythm O2 · 2022Article
- The validity of current implantable cardioverter-defibrillator guidelines in a real-world population of adults with congenital heart disease: A single-center experience.International journal of cardiology. Congenital heart disease · 2022Article
- An Evaluation of the Association between Quality of Life and Psychological Issues in Patients with Automated Implantable Cardioverter Defibrillator.Journal of caring sciences · 2022Article
- Sacubitril/valsartan versus angiotensin inhibitors and arrhythmia endpoints in heart failure with reduced ejection fraction.Heart rhythm O2 · 2021Article
- Myocardial strain assessment using cardiovascular magnetic resonance imaging in recipients of implantable cardioverter defibrillators.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2021Article
- Ventricular Arrhythmias in Ischemic Cardiomyopathy-New Avenues for Mechanism-Guided Treatment.Cells · 2021Review
- Risk of subsequent ventricular arrhythmia is higher in primary prevention patients with implantable cardioverter defibrillator than in secondary prevention patients.BMC cardiovascular disorders · 2019Article
- Appropriateness of Prescription and Safety of Wearable Cardioverter Defibrillators: A Single-center Experience.Cureus · 2019Article
- Quantification of Electromechanical Coupling to Prevent Inappropriate Implantable Cardioverter-Defibrillator Shocks.JACC. Clinical electrophysiology · 2019Article
- Epicardial ablation in genetic cardiomyopathies: a new frontier.European heart journal supplements : journal of the European Society of Cardiology · 2019Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Large-scale implantable cardioverter defibrillator (ICD) trials have unequivocally shown a reduction in mortality in appropriately selected patients with heart failure and depressed left ventricular function. However, there is a strong association between shocks and increased mortality in ICD recipients. It is unclear if shocks are merely a marker of a more severe cardiovascular disease or directly contribute to the increase in mortality. The aim of this review is to examine the relationship between ICD shocks and mortality, and explore possible mechanisms. Data examining the effect of shocks in the absence of spontaneous arrhythmias as well as studies of non-shock therapy and strategies to reduce shocks are analysed to try and disentangle the shocks versus substrate debate.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.