ArticleIranian journal of pediatrics2016
Changes of Platelet Indices in Juvenile Idiopathic Arthritis in Acute Phase and After Two Months Treatment.
Article in Iranian journal of pediatrics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Article
- Article
- Platelet Indices as Diagnostic Marker for Kawasaki Disease.Chonnam medical journal · 2022Article
- Which hematological markers have predictive value as early indicators of severe COVID-19 cases in the emergency department?Turkish journal of medical sciences · 2021Article
- Platelet Glycoprotein Ib α-Chain as a Putative Therapeutic Target for Juvenile Idiopathic Arthritis: A Mendelian Randomization Study.Arthritis & rheumatology (Hoboken, N.J.) · 2021Article
- Evaluation of Plateletcrit and Platelet Distribution Width in Patients with Non-Alcoholic Fatty Liver Disease: A Retrospective Chart Review Study.Medical science monitor : international medical journal of experimental and clinical research · 2019Article
- Mean Platelet Volume (MPV) as an indicator of disease activity and severity in lupus.F1000Research · 2017Article
- Mean Platelet Volume and Immature Platelet Fraction in Autoimmune Disorders.Frontiers in medicine · 2017Review
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6 authors.
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Abstract
backgroundVarious indices have been raised as predictors of activity and severity of juvenile idiopathic arthritis.
objectivesThis study was conducted to investigate the changes of platelet indices in acute phase and two months after treatment in these patients. PATIENTS AND
methodsIn a cohort study, platelet count, mean platelet volume (MPV), platelet distribution width (PDW), plateletcrit (PCT) were evaluated in children referred to children's medical center, Tehran due to juvenile idiopathic arthritis from March 2013 to March 2014 during the acute phase and two months after standard treatment. The statistical data were analyzed by SPSS 19 software, and the significance level was set as P < 0.05.
resultsIn this study, 55 children (24 boys and 31 girls) with mean ± SD age of 7.50 ± 3.35 years were studied. The mean ± SD value of platelet count was 441872.7 ± 151836.9 in the acute phase and reached 395418.2 ± 119601.6 two months after treatment (P = 0.01). The mean ± SD PCT in the acute phase of various subtypes of the disease was 0.32 ± 0.11, which reached 0.29 ± 0.10 after treatment (P = 0.09). However, the PDW range in different subtypes of the disease reached 13.4 ± 8.0 from 13.9 ± 2.9 and MPV reached 8.7 ± 0.9 from 8.8 ± 1.1 after treatment, but they were not significantly different from the results in the acute phase (P = 0.5).
conclusionsPlatelet count is one of the most remarkable indices in JIA. Evaluation of PCT can also help determine the severity of the inflammatory process in the follow-up and treatment process.
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