Evidence map›Paper›PMID 27616708›Full record

ArticleBioinformatics (Oxford, England)2017

ImmuneDB: a system for the analysis and exploration of high-throughput adaptive immune receptor sequencing data.

Aaron M Rosenfeld, Wenzhao Meng, Eline T Luning Prak, Uri Hershberg

Abstract read
In one paragraph

Article in Bioinformatics (Oxford, England), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. AI-Driven BCR Modeling for Precision Immunology.International journal of molecular sciences · 2026
    Review
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  17. The Pipeline Repertoire for Ig-Seq Analysis.Frontiers in immunology · 2019
    Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Aaron M RosenfeldSchool of Biomedical Engineering Science and Health Systems, Drexel University, Philadelphia, PA 19104, USA.
Wenzhao MengDepartment of Pathology and Laboratory Medicine Perelman School of Medicine, University of Pennsylvania, Philadelphia, 19104 PA, USA.
Eline T Luning PrakDepartment of Pathology and Laboratory Medicine Perelman School of Medicine, University of Pennsylvania, Philadelphia, 19104 PA, USA.
Uri HershbergSchool of Biomedical Engineering Science and Health Systems, Drexel University, Philadelphia, PA 19104, USA.

Funding

Transcriptomics and Repertoire ProfilingP01AI106697 · NIAID · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Donna L. Farber · 2013 to 2026
$31.3M
NIAID NIH HHS P01 AI106697
6 · The paper itself

Abstract

As high-throughput sequencing of B cells becomes more common, the need for tools to analyze the large quantity of data also increases. This article introduces ImmuneDB, a system for analyzing vast amounts of heavy chain variable region sequences and exploring the resulting data. It can take as input raw FASTA/FASTQ data, identify genes, determine clones, construct lineages, as well as provide information such as selection pressure and mutation analysis. It uses an industry leading database, MySQL, to provide fast analysis and avoid the complexities of using error prone flat-files. AVAILABILITY AND IMPLEMENTATION: ImmuneDB is freely available at http://immunedb.comA demo of the ImmuneDB web interface is available at: http://immunedb.com/demo CONTACT: Uh25@drexel.eduSupplementary information: Supplementary data are available at Bioinformatics online.

Indexed as

SoftwareAnimalsHigh-Throughput Nucleotide SequencingHumansReceptors, ImmunologicSequence Analysis, DNAReceptors, Immunologic

Identifiers

PMID27616708
PMCPMC5254080

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.