Evidence map›Paper›PMID 27616613›Full record

ArticleCardiovascular pathology : the official journal of the Society for Cardiovascular Pathology

Paraffin processing of stented arteries using a postfixation dissolution of metallic and polymeric stents.

Ilia Fishbein, Tre Welch, David T Guerrero, Ivan S Alferiev, Richard F Adamo, Michael Chorny, Rohit K Gupte, Yanqing Tang, Robert J Levy

Abstract read
In one paragraph

Article in Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
  2. Article
  3. Article
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  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ilia FishbeinThe Children's Hospital of Philadelphia, Philadelphia, PA, USA; Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. Electronic address: fishbein@email.chop.edu.
Tre WelchDepartment of Cardio-Thoracic Surgery, University of Texas, Dallas, Richardson, TX, USA.
David T GuerreroThe Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Ivan S AlferievThe Children's Hospital of Philadelphia, Philadelphia, PA, USA; Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Richard F AdamoThe Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Michael ChornyThe Children's Hospital of Philadelphia, Philadelphia, PA, USA; Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Rohit K GupteThe Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Yanqing TangThe Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Robert J LevyThe Children's Hospital of Philadelphia, Philadelphia, PA, USA; Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.

Funding

Uniform field controlled magnetic cell targeting to stentsR01HL111118 · NHLBI · CHILDREN'S HOSP OF PHILADELPHIA · PI CHORNY, MICHAEL · 2012 to 2016
$2.1M
NHLBI NIH HHS R01 HL111118
6 · The paper itself

Abstract

Studying the morphology of the arterial response to endovascular stent implantation requires embedding the explanted stented artery in rigid materials such as poly(methyl methacrylate) to enable sectioning through both the in situ stent and the arterial wall, thus maintaining the proper anatomic relationships. This is a laborious, time-consuming process. Moreover, the technical quality of stained plastic sections is typically suboptimal and, in some cases, precludes immunohistochemical analysis. Here we describe a novel technique for dissolution of metallic and plastic stents that is compatible with subsequent embedding of "destented" arteries in paraffin, fine sectioning, major staining protocols, and immunohistochemistry.

Indexed as

StentsAnimalsCoronary VesselsImmunohistochemistryMaleModels, AnimalParaffin EmbeddingPolyestersRatsRats, Sprague-DawleySolubilityStaining and LabelingStainless SteelTissue FixationPolyesterspoly(lactide)Stainless SteelArterial tissueHistological processingImmunohistochemistryParaffin embeddingStents

Identifiers

PMID27616613
PMCPMC5101146

What OpenQuestion holds

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LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.