Evidence map›Paper›PMID 27616350›Full record

ArticleAdvanced healthcare materials2016

Fusing Sensor Paradigms to Acquire Chemical Information: An Integrative Role for Smart Biopolymeric Hydrogels.

Eunkyoung Kim, Yi Liu, Hadar Ben-Yoav, Thomas E Winkler, Kun Yan, Xiaowen Shi, Jana Shen, Deanna L Kelly, Reza Ghodssi, William E Bentley and 1 more

Open access · greenAbstract read
In one paragraph

Article in Advanced healthcare materials, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
3.8field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Catechol-Based Hydrogel for Chemical Information Processing.Biomimetics (Basel, Switzerland) · 2017
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 3 countries.

Eunkyoung KimInstitute for Biosystems and Biotechnology Research, University of Maryland, College Park, MD, 20742, USA.
Yi LiuInstitute for Biosystems and Biotechnology Research, University of Maryland, College Park, MD, 20742, USA.
Hadar Ben-YoavDepartment of Biomedical Engineering, Ben-Gurion University of the Negev, Beer Sheva, 8410501, Israel.
Thomas E WinklerInstitute for Systems Research, University of Maryland, College Park, MD, 20742, USA.
Kun YanSchool of Resource and Environmental Science, Hubei Biomass-Resource Chemistry Environmental Biotechnology Key Laboratory, Wuhan University, Wuhan, 430079, China.
Xiaowen ShiSchool of Resource and Environmental Science, Hubei Biomass-Resource Chemistry Environmental Biotechnology Key Laboratory, Wuhan University, Wuhan, 430079, China.
Jana ShenDepartment of Pharmaceutical Sciences, School of Pharmacy, University of Maryland, Baltimore, MD, 21201, USA.
Deanna L KellyMaryland Psychiatric Research Center, University of Maryland School of Medicine, Baltimore, MD, 21228, USA.
Reza GhodssiInstitute for Systems Research, University of Maryland, College Park, MD, 20742, USA.
William E BentleyInstitute for Biosystems and Biotechnology Research, University of Maryland, College Park, MD, 20742, USA.
Gregory F PayneInstitute for Biosystems and Biotechnology Research, University of Maryland, College Park, MD, 20742, USA. gpayne@umd.edu.
University of Maryland, College Park · USUniversity of Maryland, Baltimore · USWuhan University · CNBen-Gurion University of the Negev · IL

Funding

Microsystem Development for Clozapine Monitoring in SchizophreniaR56MH105571 · NIMH · UNIVERSITY OF MARYLAND BALTIMORE · PI GHODSSI, REZA, KELLY, DEANNA L · 2015 to 2016
$741k
NIMH NIH HHS R56 MH105571
6 · The paper itself

Abstract

The Information Age transformed our lives but it has had surprisingly little impact on the way chemical information (e.g., from our biological world) is acquired, analyzed and communicated. Sensor systems are poised to change this situation by providing rapid access to chemical information. This access will be enabled by technological advances from various fields: biology enables the synthesis, design and discovery of molecular recognition elements as well as the generation of cell-based signal processors; physics and chemistry are providing nano-components that facilitate the transmission and transduction of signals rich with chemical information; microfabrication is yielding sensors capable of receiving these signals through various modalities; and signal processing analysis enhances the extraction of chemical information. The authors contend that integral to the development of functional sensor systems will be materials that (i) enable the integrative and hierarchical assembly of various sensing components (for chemical recognition and signal transduction) and (ii) facilitate meaningful communication across modalities. It is suggested that stimuli-responsive self-assembling biopolymers can perform such integrative functions, and redox provides modality-spanning communication capabilities. Recent progress toward the development of electrochemical sensors to manage schizophrenia is used to illustrate the opportunities and challenges for enlisting sensors for chemical information processing.

Indexed as

AnimalsBiopolymersBiosensing TechniquesHumansHydrogelsBiopolymersHydrogelsbiofabricationselectrodepositionshydrogelsinformation processingredox biology

Identifiers

PMID27616350
PMCPMC5485850
OpenAlexW2520242324

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.