ReviewNeurologia medico-chirurgica2016
Interactive Bio-feedback Therapy Using Hybrid Assistive Limbs for Motor Recovery after Stroke: Current Practice and Future Perspectives.
Review in Neurologia medico-chirurgica, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed, 37 citations in OpenAlex.
- Effect of early hybrid assistive limb assisted rehabilitation on functional outcomes and patient satisfaction after total knee arthroplasty: a randomized controlled trial.Journal of rehabilitation medicine · 2026Trial
- Home-based Hybrid Assistive Limb Lumbar Type Telerehabilitation in Spinocerebellar Ataxias: A Nonrandomized Open-label Trial.Cerebellum (London, England) · 2025Trial
- Effects of Supplemental Robot-Assisted Knee Flexion Exercise After Total Knee Arthroplasty: A Randomized Controlled Clinical Study.Journal of musculoskeletal & neuronal interactions · 2025Trial
- Postoperative gait training using the Hybrid Assistive Limb for pediatric spinal intramedullary cavernous malformation: illustrative case.Journal of neurosurgery. Case lessons · 2026Article
- Robot-assisted gait training using a robotic exoskeleton during inpatient rehabilitation in acute Guillain-Barré Syndrome.BMJ case reports · 2026Article
- Article
- Intention-driven ankle exoskeleton training acutely alters swing foot clearance distribution: a preliminary study.Frontiers in neurorobotics · 2026Article
- Expectations for Robotic Support in Acute Cardiac Rehabilitation of Older Patients - Towards a New Era.Circulation reports · 2025Article
- Safety and Selection Criteria of Single-joint Hybrid Assistive Limb for Upper Limb Paralysis After Stroke: A Phase I Trial.Neurologia medico-chirurgica · 2025Article
- Improving Spasticity by Using Botulin Toxin: An Overview Focusing on Combined Approaches.Brain sciences · 2024Review
- Article
- Article
- Effect of Robot-assisted Rehabilitation to Botulinum Toxin A Injection for Upper Limb Disability in Patients with Chronic Stroke: A Case Series and Systematic Review.Neurologia medico-chirurgica · 2022Observational
- Alteration of muscle activity during voluntary rehabilitation training with single-joint Hybrid Assistive Limb (HAL) in patients with shoulder elevation dysfunction from cervical origin.Frontiers in neuroscience · 2022Article
- Involvement of the Rostromedial Prefrontal Cortex in Human-Robot Interaction: fNIRS Evidence From a Robot-Assisted Motor Task.Frontiers in neurorobotics · 2022Article
- Article
- Potential role of biofeedback therapy for Parkinson's disease.Neural regeneration research · 2021Article
- Efficacy and Safety Study of Wearable Cyborg HAL (Hybrid Assistive Limb) in Hemiplegic Patients With Acute Stroke (EARLY GAIT Study): Protocols for a Randomized Controlled Trial.Frontiers in neuroscience · 2021Article
- Feasibility of Robot-assisted Rehabilitation in Poststroke Recovery of Upper Limb Function Depending on the Severity.Neurologia medico-chirurgica · 2020Article
- Biofeedback Core Exercise Using Hybrid Assistive Limb for Physical Frailty Patients With or Without Parkinson's Disease.Frontiers in neurology · 2020Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Interactive bio-feedback (iBF) was initially developed for the rehabilitation of motor function in patients with neurological disorders, and subsequently yielded the development of the hybrid assistive limb (HAL). Here, we provide a review of the theory underlying HAL treatment as well as our clinical experience and recommendations for future clinical studies using HAL in acute stroke patients. We performed a PubMed-based literature search, a retrospective data review of our acute stroke case series, and included a sample case report of our findings. Given past animal studies and functional imaging results, iBF therapy using the HAL in the acute phase of stroke seems an appropriate approach for preventing learned non-use and interhemispheric excitation imbalances. iBF therapy may furthermore promote appropriate neuronal network reorganization. Based on experiences in our stroke center, HAL rehabilitation is a safe and effective treatment modality for recovering motor impairments after acute stroke, and allows the design of tailored rehabilitation programs for individual patients. iBF therapy through the HAL system seems to be an effective and promising approach to stroke rehabilitation; however, the superiority of this treatment to conventional rehabilitation remains unclear. Further clinical studies are warranted. Additionally, the formation of a patient registry will permit a meta-analysis of HAL cases and address the problems associated with a controlled trial (e.g., the heterogeneity of an acute stroke cohort). The development of robotic engineering will improve the efficacy of HAL rehabilitation and has the potential to standardize patient rehabilitation practice.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.