ArticleEuropean journal of applied physiology2016
Heritability of heart rate recovery and vagal rebound after exercise.
Article in European journal of applied physiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 27 citations in OpenAlex.
- Utility of Heart Rate Variability and Exertional Task Completion During Recovery of Mild Traumatic Brain Injury in Active Duty Service Members.Military medicine · 2026Article
- Sleep disruption from inhalation of biomass smoke: a basis for coincident hypertension?Particle and fibre toxicology · 2025Article
- Conventional and genetic associations between resting heart rate, cardiac morphology and function as assessed by magnetic resonance imaging: Insights from the UK biobank population study.Frontiers in cardiovascular medicine · 2023Article
- Heart Rate Recovery (HRR) Is Not a Singular Predictor for Physical Fitness.International journal of environmental research and public health · 2022Article
- Cardiovascular response to physical exercise and the risk of Internet addiction in 15-16-year-old adolescents.Journal of behavioral addictions · 2021Article
- Maturation of the Cardiac Autonomic Nervous System Activity in Children and Adolescents.Journal of the American Heart Association · 2021Article
- Compassion Is Not a Benzo: Distinctive Associations of Heart Rate Variability With Its Empathic and Action Components.Frontiers in neuroscience · 2021Article
- Heart rate recovery in normal and obese males with and without parental history of cardiovascular disease.Journal of family medicine and primary care · 2020Article
- Genetics and the heart rate response to exercise.Cellular and molecular life sciences : CMLS · 2019Review
- Cardiac Vagus and Exercise.Physiology (Bethesda, Md.) · 2019Review
- Perspectives on two temperamental biases.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2018Review
- Genetic study links components of the autonomous nervous system to heart-rate profile during exercise.Nature communications · 2018Article
- Vagal Tank Theory: The Three Rs of Cardiac Vagal Control Functioning - Resting, Reactivity, and Recovery.Frontiers in neuroscience · 2018Article
- Long-term intra-individual reproducibility of heart rate dynamics during exercise and recovery in the UK Biobank cohort.PloS one · 2017Article
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe prognostic power of heart rate recovery (HRR) after exercise has been well established but the exact origin of individual differences in HRR remains unclear. This study aims to estimate the heritability of HRR and vagal rebound after maximal exercise in adolescents. Furthermore, the role of voluntary regular exercise behavior (EB) in HRR and vagal rebound is tested.
methods491 healthy adolescent twins and their siblings were recruited for maximal exercise testing, followed by a standardized cooldown with measurement of the electrocardiogram and respiratory frequency. Immediate and long-term HRR (HRR60 and HRR180) and vagal rebound (heart rate variability in the respiratory frequency range) were assessed 1 and 3 min after exercise. Multivariate twin modeling was used to estimate heritability of all measured variables and to compute the genetic contribution to their covariance.
resultsHeritability of HRR60, HRR180 and immediate and long-term vagal rebound is 60 % (95 % CI: 48-67), 65 % (95 % CI: 54-73), 23 % (95 % CI: 11-35) and 3 % (95 % CI: 0-11), respectively. We find evidence for two separate genetic factors with one factor influencing overall cardiac vagal control, including resting heart rate and respiratory sinus arrhythmia, and a specific factor for cardiac vagal exercise recovery. EB was only modestly associated with resting heart rate (r = -0.27) and HRR (rHRR60 = 0.10; rHRR180 = 0.19) with very high genetic contribution to these associations (88-91 %).
conclusionsIndividual differences in HRR and immediate vagal rebound can to a large extent be explained by genetic factors. These innate cardiac vagal exercise recovery factors partly reflect the effects of heritable differences in EB.
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