Evidence map›Paper›PMID 27614613›Full record

ArticleJournal of biomechanics2016

The role of anisotropic expansion for pulmonary acinar aerosol deposition.

Philipp Hofemeier, Josué Sznitman

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of biomechanics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. [Numerical simulation on the deposition characteristics of inhaled particles in human pulmonary acinus region under the influence of multi-factors].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2020
    Article
  7. Review
  8. MultiscaleCurrent opinion in biomedical engineering · 2019
    Article
  9. Targeting inhaled fibers to the pulmonary acinus: Opportunities for augmented delivery from in silico simulations.European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences · 2019
    Article
  10. [Progress on numerical simulation of the deposition of inhaled particles in human pulmonary acinus region].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2019
    Review
  11. Modeling Airflow and Particle Deposition in a Human Acinar Region.Computational and mathematical methods in medicine · 2019
    Article
  12. One (sub-)acinus for all: Fate of inhaled aerosols in heterogeneous pulmonary acinar structures.European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences · 2018
    Review
  13. Transport of ellipsoid fibers in oscillatory shear flows: Implications for aerosol deposition in deep airways.European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences · 2018
    Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Philipp HofemeierDepartment of Biomedical Engineering, Technion - Israel Institute of Technology, Haifa 32000, Israel.
Josué SznitmanDepartment of Biomedical Engineering, Technion - Israel Institute of Technology, Haifa 32000, Israel. Electronic address: sznitman@bm.technion.ac.il.

Funding

European Research Council 677772
6 · The paper itself

Abstract

Lung deformations at the local pulmonary acinar scale are intrinsically anisotropic. Despite progress in imaging modalities, the true heterogeneous nature of acinar expansion during breathing remains controversial, where our understanding of inhaled aerosol deposition still widely emanates from studies under self-similar, isotropic wall motions. Building on recent 3D models of multi-generation acinar networks, we explore in numerical simulations how different hypothesized scenarios of anisotropic expansion influence deposition outcomes of inhaled aerosols in the acinar depths. While the broader range of particles acknowledged to reach the acinar region (d

Indexed as

AerosolsModels, BiologicalRespirationAnisotropyComputer SimulationDiffusionLungParticle SizeAerosolsAerosol depositionAnisotropic expansionCFDNumerical simulationsParticle transportPulmonary acinus

Identifiers

PMID27614613
PMCPMC5075582

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.