Evidence map›Paper›PMID 27614234›Full record

ArticleGenome biology and evolution2016

Role of Host-Driven Mutagenesis in Determining Genome Evolution of Sigma Virus (DMelSV; Rhabdoviridae) in Drosophila melanogaster.

Helen Piontkivska, Luis F Matos, Sinu Paul, Brian Scharfenberg, William G Farmerie, Michael M Miyamoto, Marta L Wayne

Open access · goldAbstract read
In one paragraph

Article in Genome biology and evolution, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
6.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Explaining Pathogenicity of Congenital Zika and Guillain-Barré Syndromes: Does Dysregulation of RNA Editing Play a Role?BioEssays : news and reviews in molecular, cellular and developmental biology · 2019
    Article
  7. Article
  8. Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Helen PiontkivskaDepartment of Biological Sciences and School of Biomedical Sciences, Kent State University, Kent, OH opiontki@kent.edu.
Luis F MatosDepartment of Entomology & Nematology, University of Florida, Gainesville, FL Department of Biology, Eastern Washington University, Cheney, WA.
Sinu PaulDepartment of Biological Sciences and School of Biomedical Sciences, Kent State University, Kent, OH Division of Vaccine Discovery, La Jolla Institute for Allergy and Immunology, La Jolla, CA.
Brian ScharfenbergDepartment of Biological Sciences and School of Biomedical Sciences, Kent State University, Kent, OH Ohio University Heritage College of Osteopathic Medicine, Athens, OH.
William G FarmerieInterdisciplinary Center for Biotechnology Research University of Florida, Gainesville, FL.
Michael M MiyamotoDepartment of Biology, University of Florida, Gainesville, FL.
Marta L WayneDepartment of Biology, University of Florida, Gainesville, FL Emerging Pathogens Institute University of Florida, Gainesville, FL.
University of Florida · US

Funding

Sigma virus in Drosophila: a model system for the evolution of virulenceR01GM083192 · NIGMS · UNIVERSITY OF FLORIDA · PI WAYNE, MARTA L · 2009 to 2012
$1.2M
Molecular Evolution of Viral Epitopes: Adaptive Evolution of EvasionR15GM086782 · NIGMS · KENT STATE UNIVERSITY · PI PIONTKIVSKA, HELEN · 2010 to 2010
$205k
NIGMS NIH HHS R01 GM083192NIGMS NIH HHS R15 GM086782
6 · The paper itself

Abstract

Sigma virus (DMelSV) is ubiquitous in natural populations of Drosophila melanogaster. Host-mediated, selective RNA editing of adenosines to inosines (ADAR) may contribute to control of viral infection by preventing transcripts from being transported into the cytoplasm or being translated accurately; or by increasing the viral genomic mutation rate. Previous PCR-based studies showed that ADAR mutations occur in DMelSV at low frequency. Here we use SOLiD

Indexed as

Genome, ViralMutation RateAdenosineAnimalsDrosophila melanogasterHost-Pathogen InteractionsInosineInsect VirusesMutagenesisPolymorphism, GeneticRhabdoviridaeRNA EditingAdenosineInosineADARimmunitymutationphylogenyquasispeciesRNA virus

Identifiers

PMID27614234
PMCPMC5630973
OpenAlexW2512385287

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.