Evidence map›Paper›PMID 27614201›Full record

ReviewJournal of radiation research2016

Neutron relative biological effectiveness in Hiroshima and Nagasaki atomic bomb survivors: a critical review.

Masao S Sasaki, Satoru Endo, Masaharu Hoshi, Taisei Nomura

Open access · goldAbstract readReview
In one paragraph

Review in Journal of radiation research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
  3. Neutron Radiobiology and Dosimetry.Radiation research · 2021
    Article
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Masao S SasakiKyoto University and National Institute of Biomedical Innovation, Health and Nutrition, 17-12 Shironosato, Nagaokakyo-shi, Kyoto 617-0835, Japan masao.sasaki.43n@st.kyoto-u.ac.jp.
Satoru EndoQuantum Energy Application, Graduate School of Engineering, Hiroshima University, 1-4-1 Kagamiyama, Higashi-hiroshima, Hiroshima 739-8527, Japan.
Masaharu HoshiInstitute for Peace Science, Hiroshima University, 1-1-89 Higashisenda, Naka-ku, Hiroshima 730-0053, Japan.
Taisei NomuraNational Institute of Biomedical Innovation, Health and Nutrition, 7-6-8 Saito-Asagi, Ibaraki-shi, Osaka 567-0086, Japan.
Hiroshima University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The calculated risk of cancer in humans due to radiation exposure is based primarily on long-term follow-up studies, e.g. the life-span study (LSS) on atomic bomb (A-bomb) survivors in Hiroshima and Nagasaki. Since A-bomb radiation consists of a mixture of γ-rays and neutrons, it is essential that the relative biological effectiveness (RBE) of neutrons is adequately evaluated if a study is to serve as a reference for cancer risk. However, the relatively small neutron component hampered the direct estimation of RBE in LSS data. To circumvent this problem, several strategies have been attempted, including dose-independent constant RBE, dose-dependent variable RBE, and dependence on the degrees of dominance of intermingled γ-rays. By surveying the available literature, we tested the chromosomal RBE of neutrons as the biological endpoint for its equivalence to the microdosimetric quantities obtained using a tissue-equivalent proportional counter (TEPC) in various neutron fields. The radiation weighting factor, or quality factor, Q

Indexed as

Neoplasms, Radiation-InducedNuclear WarfareRelative Biological EffectivenessChromosomesDose-Response Relationship, RadiationHumansJapanLeukemia, Radiation-InducedNeutronsRadiation DosageRadiometryRiskTreatment OutcomeWorld War IIatomic bomb survivorcancer riskchromosomal effectivenessmicrodosimetrymixed-radiation fieldneutron RBE

Identifiers

PMID27614201
PMCPMC5137296
OpenAlexW2514396163

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.