Evidence map›Paper›PMID 27613968›Full record

ArticleAddiction (Abingdon, England)2017

What happened to the HIV epidemic among non-injecting drug users in New York City?

Don C Des Jarlais, Kamyar Arasteh, Courtney McKnight, Jonathan Feelemyer, Aimee N C Campbell, Susan Tross, Hannah L F Cooper, Holly Hagan, David C Perlman

Open access · greenAbstract read
In one paragraph

Article in Addiction (Abingdon, England), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. A mixed methods study of HIV-related services in buprenorphine treatment.Substance abuse treatment, prevention, and policy · 2017
    Article
  7. Article
  8. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Don C Des JarlaisIcahn School of Medicine at Mount Sinai, New York, NY, USA.
Kamyar ArastehIcahn School of Medicine at Mount Sinai, New York, NY, USA.
Courtney McKnightIcahn School of Medicine at Mount Sinai, New York, NY, USA.
Jonathan FeelemyerIcahn School of Medicine at Mount Sinai, New York, NY, USA.
Aimee N C CampbellNew York State Psychiatric Institute, Department of Psychiatry, Columbia University Medical Center, New York, NY, USA.
Susan TrossNew York State Psychiatric Institute, Department of Psychiatry, Columbia University Medical Center, New York, NY, USA.
Hannah L F CooperDepartment of Behavioral Sciences and Health Education, Rollins School of Public Health, Emory University, Atlanta, GA, USA.
Holly HaganCollege of Nursing, New York University, New York, NY, USA.
David C PerlmanIcahn School of Medicine at Mount Sinai, New York, NY, USA.
Icahn School of Medicine at Mount Sinai · USNew York Psychoanalytic Society and Institute · USEmory University · USNew York University · US

Funding

The Statistics, Data Science, and Data Management (SDM) CoreP30MH043520 · NIMH · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI MILTON L WAINBERG · 2003 to 2026
$48.2M
Transdisciplinary Theoretical Svnthesis and Development CoreP30DA011041 · NIDA · NEW YORK UNIVERSITY · PI Holly Hagan · 1998 to 2026
$38.9M
Risk Factors for HIV/AIDS in Drug UsersR01DA003574 · NIDA · NEW YORK UNIVERSITY · PI DES JARLAIS, DON C, MCKNIGHT, COURTNEY · 1986 to 2025
$16.2M
Evaluating ART for All HIV Seropositives: Can it work with the hardest cases?R01DA035707 · NIDA · ST. LUKE'S-ROOSEVELT INST FOR HLTH SCIS · PI CAMPBELL, AIMEE N, DES JARLAIS, DON C · 2013 to 2017
$3.1M
NIDA NIH HHS P30 DA011041NIDA NIH HHS R01 DA003574NIDA NIH HHS R01 DA035707NIMH NIH HHS P30 MH043520
6 · The paper itself

Abstract

BACKGROUND AND

aimsHIV has reached high prevalence in many non-injecting drug user (NIDU) populations. The aims of this study were to (1) examine the trend in HIV prevalence among non-injecting cocaine and heroin NIDUs in New York City, (2) identify factors potentially associated with the trend and (3) estimate HIV incidence among NIDUs.

designSerial-cross sectional surveys of people entering drug treatment programs. People were permitted to participate only once per year, but could participate in multiple years.

settingMount Sinai Beth Israel drug treatment programs in New York City, USA.

participantsWe recruited 3298 non-injecting cocaine and heroin users from 2005 to 2014. Participants were 78.7% male, 6.1% white, 25.7% Hispanic and 65.8% African American. Smoking crack cocaine was the most common non-injecting drug practice. MEASURES: Trend tests were used to examine HIV prevalence, demographics, drug use, sexual behavior and use of antiretroviral treatment (ART) by calendar year; χ

findingsHIV prevalence declined approximately 1% per year (P < 0.001), with a decline from 16% in 2005-10 to 8% in 2011-14 (P < 0.001). The percentages of participants smoking crack and having multiple sexual partners declined and the percentage of HIV-positive people on ART increased. HIV incidence among repeat participants was 1.2 per 1000 person-years (95% confidence interval = 0.03/1000-7/1000).

conclusionsHIV prevalence has declined and a high percentage of HIV-positive non-injecting drug users (NIDUs) are receiving antiretroviral treatment, suggesting an end to the HIV epidemic among NIDUs in New York City. These results can be considered a proof of concept that it is possible to control non-injecting drug use related sexual transmission HIV epidemics.

Indexed as

AdultAnti-Retroviral AgentsCocaine-Related DisordersComorbidityCross-Sectional StudiesDrug UsersEpidemicsFemaleHeroin DependenceHIV InfectionsHumansIncidenceMaleMiddle AgedNew York CityPrevalenceAnti-Retroviral AgentsCrack-cocaineHIVNew York Citynon-injection drug useprevalence/incidencesubstance use/abuse

Identifiers

PMID27613968
PMCPMC5233554
OpenAlexW2520727922

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.