Evidence map›Paper›PMID 27613714›Full record

ArticleToxicological sciences : an official journal of the Society of Toxicology2016

Disposition of the Emerging Brominated Flame Retardant, 2-Ethylhexyl 2,3,4,5-Tetrabromobenzoate, in Female SD Rats and Male B6C3F1 Mice: Effects of Dose, Route, and Repeated Administration.

Gabriel A Knudsen, J Michael Sanders, Linda S Birnbaum

Abstract readComparative Study
In one paragraph

Article in Toxicological sciences : an official journal of the Society of Toxicology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Gabriel A KnudsenNCI Laboratory of Toxicology and Toxicokinetics, Research Triangle Park, North Carolina gabriel.knudsen@nih.gov.
J Michael SandersNCI Laboratory of Toxicology and Toxicokinetics, Research Triangle Park, North Carolina.
Linda S BirnbaumNCI Laboratory of Toxicology and Toxicokinetics, Research Triangle Park, North Carolina.

Funding

Studies of the fate of environmental contaminants in humans and animalsZIABC011476 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI BIRNBAUM, LINDA · 2013 to 2019
$5.8M
Intramural NIH HHS ZIA BC011476
6 · The paper itself

Abstract

2-Ethylhexyl-2,3,4,5-tetrabromobenzoate (EH-TBB; MW 549.92 g/mol; CAS 183658-27-7) is a brominated component of flame retardant mixtures used as substitutes for some PBDEs. EH-TBB is added to various consumer products, including polyurethane foams, and has been detected in humans. The present study characterized the fate of EH-TBB in rodents. [

Indexed as

Administration, OralAnimalsBenzoatesBiotransformationDrug Administration ScheduleFecesFemaleFlame RetardantsGastrointestinal AbsorptionInjections, IntravenousMaleMiceModels, BiologicalRats, Sprague-DawleyRenal EliminationRisk Assessment2-ethylhexyl 2,3,4,5-tetrabromobenzoateBenzoatesFlame Retardants2-Ethylhexyl 2,3,4,5-Tetrabromobenzoatedispositionmetabolism.

Identifiers

PMID27613714
PMCPMC5139073

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.