ReviewEuropean journal of applied physiology2016
An integrated view on the oxygenation responses to incremental exercise at the brain, the locomotor and respiratory muscles.
Review in European journal of applied physiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
34 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Cerebral and muscle tissue oxygenation during exercise in healthy adults: A systematic review.Journal of sport and health science · 2024Pooled it
- Plasma Nucleotide Dynamics during Exercise and Recovery in Highly Trained Athletes and Recreationally Active Individuals.BioMed research international · 2018Trial
- Network integration and evolution of organ systems interactions during incremental exercise.European journal of applied physiology · 2026Article
- Visually identified breakpoints in muscle oxygen saturation are not equivalent to ventilatory thresholds in national-level triathletes.European journal of applied physiology · 2026Article
- Networks of respiratory-muscular coupling in exercise and fatigue in young adults.Physiological reports · 2026Article
- Effect of Roxadustat on Cardiometabolism in Healthy Individuals (ROXACardioMeta): Protocol for a Double-Blind, Placebo-Controlled and Randomised Cross-Over Trial.Methods and protocols · 2026Article
- Compensatory Oxygenation Changes in Non-active and Active Muscles During Incremental Exercise in Healthy Adults.Advances in experimental medicine and biology · 2026Article
- Effects of fractional inspired OPhysiological reports · 2025Article
- Physiological Predictors of Peak Velocity in the VAM-EVAL Incremental Test and the Role of Kinematic Variables in Running Economy in Triathletes.Sports (Basel, Switzerland) · 2025Article
- Cardiac workload and skeletal muscle oxygenation during incremental exercise in healthy subjects.Physiological reports · 2025Article
- Combined effect of sprint interval training and post-exercise blood flow restriction on muscle deoxygenation responses during ramp incremental cycling.European journal of applied physiology · 2025Article
- The relationship and agreement between systemic and local breakpoints in locomotor and non-locomotor muscles during single-leg cycling.Frontiers in physiology · 2025Article
- The effects of endurance training on muscle oxygen desaturation during incremental exercise tests: a systematic review and meta-analysis.Frontiers in sports and active living · 2024Article
- Assessment of Intercostal Muscle Near-Infrared Spectroscopy for Estimating Respiratory Compensation Point in Trained Endurance Athletes.Sports (Basel, Switzerland) · 2023Article
- Conventional methods to prescribe exercise intensity are ineffective for exhaustive interval training.European journal of applied physiology · 2023Article
- Comparing the reliability of muscle oxygen saturation with common performance and physiological markers across cycling exercise intensity.Frontiers in sports and active living · 2023Article
- A longitudinal study on the interchangeable use of whole-body and local exercise thresholds in cycling.European journal of applied physiology · 2022Article
- A Subject-Tailored Variability-Based Platform for Overcoming the Plateau Effect in Sports Training: A Narrative Review.International journal of environmental research and public health · 2022Review
- Systemic and Quadriceps Muscle OAdvances in experimental medicine and biology · 2022Article
- Isolated finger flexor vs. exhaustive whole-body climbing tests? How to assess endurance in sport climbers?European journal of applied physiology · 2021Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In the past two decades oxygenation responses to incremental ramp exercise, measured non-invasively by means of near-infrared spectroscopy at different locations in the body, have advanced the insights on the underpinning mechanisms of the whole-body pulmonary oxygen uptake ([Formula: see text]) response. In healthy subjects the complex oxygenation responses at the level of locomotor and respiratory muscles, and brain were simplified and quantified by the detection of breakpoints as a deviation in the ongoing response pattern as work rate increases. These breakpoints were located in a narrow intensity range between 75 and 90 % of the maximal [Formula: see text] and were closely related to traditionally determined thresholds in pulmonary gas exchange (respiratory compensation point), blood lactate measurements (maximal lactate steady state), and critical power. Therefore, it has been assumed that these breakpoints in the oxygenation patterns at different sites in the body might be equivalent and could, therefore, be used interchangeably. In the present review the typical oxygenation responses (at locomotor and respiratory muscle level, and cerebral level) are described and a possible framework is provided showing the physiological events that might link the breakpoints at different body sites with the thresholds determined from pulmonary gas exchange and blood lactate measurements. However, despite a possible physiological association, several arguments prevent the current practical application of these breakpoints measured at a single site as markers of exercise intensity making it highly questionable whether measurements of the oxygenation response at one single site can be used as a reflection of whole-body responses to different exercise intensities.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.