ArticleEuropean journal of nuclear medicine and molecular imaging2017
Influence of blood-brain barrier permeability on O-(2-
Article in European journal of nuclear medicine and molecular imaging, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 32 citations in OpenAlex.
- The confounding effects of microvascular physiology on the uptake and diagnostic accuracy of [European journal of nuclear medicine and molecular imaging · 2026Article
- Influence of corticosteroids on contrast enhancement in patients with untreated glioblastoma.Neuro-oncology · 2025Article
- Autoradiography of Intracerebral Tumours in the Chick Embryo Model: A Feasibility Study Using Different PET Tracers.Molecular imaging and biology · 2025Article
- Radiosynthesis and biological evaluation of [European journal of nuclear medicine and molecular imaging · 2024Article
- Review
- Multiparametric Longitudinal Profiling of RCAS-tva-Induced PDGFB-Driven Experimental Glioma.Brain sciences · 2022Article
- Nuclear Medicine Imaging Procedures in Oncology.Methods in molecular biology (Clifton, N.J.) · 2021Article
- High uptake ofEJNMMI research · 2020Article
- The blood-brain barrier and blood-tumour barrier in brain tumours and metastases.Nature reviews. Cancer · 2020Review
- Investigating the effects of dexamethasone on blood-brain barrier permeability and inflammatory response following focused ultrasound and microbubble exposure.Theranostics · 2020Article
- Recurrent glioblastoma versus late posttreatment changes: diagnostic accuracy of O-(2-[18F]fluoroethyl)-L-tyrosine positron emission tomography (18F-FET PET).Neuro-oncology · 2019Article
- Influence of Dexamethasone on O-(2-[Molecular imaging and biology · 2019Article
- Suppression of Angiotensin-(1-7) on the Disruption of Blood-Brain Barrier in Rat of Brain Glioma.Pathology oncology research : POR · 2019Article
- Investigation of cis-4-[Molecular imaging and biology · 2018Article
- The Emerging Role of Amino Acid PET in Neuro-Oncology.Bioengineering (Basel, Switzerland) · 2018Review
- European research trends in nuclear medicine.Annals of nuclear medicine · 2018Review
- Hybrid MR-PET of brain tumours using amino acid PET and chemical exchange saturation transfer MRI.European journal of nuclear medicine and molecular imaging · 2018Article
- Article
- Combined FET PET/MRI radiomics differentiates radiation injury from recurrent brain metastasis.NeuroImage. Clinical · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeO-(2-
methodsF98 glioma, 9L gliosarcoma or human U87 glioblastoma cells were implanted into the striatum of 56 Fischer or RNU rats. Thereafter, animals were divided into a control group and a group receiving injections of the glucocorticoid dexamethasone (Dex). After 12-13 days of tumor growth animals received injection of Evans blue dye (EBD) to visualize BBB disturbance and underwent
resultsIn Dex treated animals EBD extravasation was significantly reduced in 9L (P < 0.001) and U87 (P = 0.008) models and showed a trend in F98 models (P = 0.053). In contrast, no significant differences of
conclusionDespite a considerable reduction of BBB permeability in rat gliomas after Dex treatment, no relevant changes of
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.