Evidence map›Paper›PMID 27613417›Full record

ArticleVirus genes2017

The genomes of three North American orthopoxviruses.

Chad Smithson, Nick Tang, Scott Sammons, Mike Frace, Dhwani Batra, Yu Li, Ginny L Emerson, Darin S Carroll, Chris Upton

Abstract read
PubMed Publisher
In one paragraph

Article in Virus genes, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
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  4. Variola virus genome sequenced from an eighteenth-century museum specimen supports the recent origin of smallpox.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2020
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Chad SmithsonDepartment of Biochemistry and Microbiology, University of Victoria, Victoria, BC, Canada.
Nick TangDepartment of Biochemistry and Microbiology, University of Victoria, Victoria, BC, Canada.
Scott SammonsThe National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia.
Mike FraceThe National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia.
Dhwani BatraThe National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia.
Yu LiThe National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia.
Ginny L EmersonThe National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia.
Darin S CarrollThe National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia.
Chris UptonDepartment of Biochemistry and Microbiology, University of Victoria, Victoria, BC, Canada. cupton@uvic.ca.ORCID http://orcid.org/0000-0002-9019-8967
Centers for Disease Control and Prevention · USUniversity of Victoria · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The complete genomes of a skunkpox, volepox, and raccoonpox virus were sequenced and annotated. Phylogenetic analysis of these genomes indicates that although these viruses are all orthopoxviruses, they form a distinct clade to the other known species. This supports the ancient divergence of the North American orthopoxviruses from other members of the orthopoxviruses. Only two open reading frames appear to be unique to this group of viruses, but a relatively small number of insertions/deletions contribute to the varied gene content of this clade. The availability of these genomes will help determine whether skunkpox and volepox viruses share the characteristics that make raccoonpox a useful vaccine vector.

Indexed as

Genome, ViralAnimalsComputational BiologyGene Expression Regulation, ViralHumansMolecular Sequence AnnotationMutationNorth AmericaOpen Reading FramesOrthopoxvirusPhylogenyPoxviridae InfectionsSequence Analysis, DNAEvolutionOrthopoxPhylogenyPoxvirusRaccoonpoxSkunkpoxVolepox

Identifiers

PMID27613417
OpenAlexW2518096075

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.