Evidence map›Paper›PMID 27613232›Full record

ReviewPaediatric respiratory reviews2017

In utero alcohol effects on foetal, neonatal and childhood lung disease.

Theresa W Gauthier, Lou Ann S Brown

Open access · hybridAbstract readReview
In one paragraph

Review in Paediatric respiratory reviews, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
5.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. The longitudinal assessment of prenatal cannabis use on neonatal outcomes.Journal of perinatology : official journal of the California Perinatal Association · 2024
    Article
  6. Fetal lung development via quantitative biomarkers from diffusion MRI and histological validation in rhesus macaques.Journal of perinatology : official journal of the California Perinatal Association · 2022
    Article
  7. Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Theresa W GauthierDepartment of Paediatrics, Division of Neonatal-Perinatal Medicine, Emory University, 2015 Uppergate Dr. NE, Atlanta, GA 30322, USA. Electronic address: tgauthi@emory.edu.
Lou Ann S BrownDepartment of Paediatrics, Division of Neonatal-Perinatal Medicine, Emory University, 2015 Uppergate Dr. NE, Atlanta, GA 30322, USA. Electronic address: lbrow03@emory.edu.
Emory University · US

Funding

THE ROLE OF TGFB IN ETHANOL MEDIATED LUNG INJURYP50AA013757 · NIAAA · EMORY UNIVERSITY · PI MARTIN, GREGORY S · 2003 to 2013
$15.7M
NIAAA NIH HHS P50 AA013757
6 · The paper itself

Abstract

Maternal alcohol use during pregnancy exposes both premature and term newborns to the toxicity of alcohol and its metabolites. Foetal alcohol exposure adversely effects the lung. In contrast to the adult "alcoholic lung" phenotype, an inability to identify the newborn exposed to alcohol in utero has limited our understanding of its effect on adverse pulmonary outcomes. This paper will review advances in biomarker development of in utero alcohol exposure. We will highlight the current understanding of in utero alcohol's toxicity to the developing lung and immune defense. Finally, we will present recent clinical evidence describing foetal alcohol's association with adverse pulmonary outcomes including bronchopulmonary dysplasia, viral infections such as respiratory syncytial virus and allergic asthma/atopy. With research to define alcohol's effect on the lung and translational studies accurately identifying the exposed offspring, the full extent of alcohol's effects on clinical respiratory outcomes of the newborn or child can be determined.

Indexed as

Alcohol DrinkingAsthmaBiomarkersBronchopulmonary DysplasiaChildFemaleGlucuronatesGlycerophospholipidsHumansImmune System DiseasesInfant, NewbornLungLung DiseasesPneumonia, ViralPregnancyPrenatal Exposure Delayed EffectsBiomarkersdiethyl sulfateethyl glucuronideGlucuronatesGlycerophospholipidsphosphatidylethanolSulfuric Acid EstersFoetal alcoholimmunityinfectionlungnewbornpregnancy

Identifiers

PMID27613232
PMCPMC5303127
OpenAlexW2514666473

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.