Evidence map›Paper›PMID 27613155›Full record

ReviewProgress in neuro-psychopharmacology & biological psychiatry2017

Contributions of the adaptive immune system to mood regulation: Mechanisms and pathways of neuroimmune interactions.

Miles Herkenham, Stacey L Kigar

Abstract readReview
In one paragraph

Review in Progress in neuro-psychopharmacology & biological psychiatry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Review
  6. Article
  7. Immunoenhancing Effects ofMarine drugs · 2022
    Article
  8. Review
  9. Review
  10. Review
  11. Article
  12. Review
  13. Review
  14. CD8Cytokine · 2019
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 2 countries.

Miles HerkenhamSection on Functional Neuroanatomy, Intramural Research Program, National Institute of Mental Health, NIH, Bethesda, MD, USA. Electronic address: herkenh@mail.nih.gov.
Stacey L KigarSection on Functional Neuroanatomy, Intramural Research Program, National Institute of Mental Health, NIH, Bethesda, MD, USA.
National Institute of Mental Health · US

Funding

Studies Of Central Nervous System Functional AnatomyZIAMH001090 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI HERKENHAM, MILES A. · 2009 to 2022
$19.3M
STUDIES OF CENTRAL NERVOUS SYSTEM FUNCTIONAL ANATOMYZ01MH001090 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI HERKENHAM, MILES A. · 1985 to 2008
$2.5M
Intramural NIH HHS Z01 MH001090Intramural NIH HHS ZIA MH001090
6 · The paper itself

Abstract

Clinical and basic studies of functional interactions between adaptive immunity, affective states, and brain function are reviewed, and the neural, humoral, and cellular routes of bidirectional communication between the brain and the adaptive immune system are evaluated. In clinical studies of depressed populations, lymphocytes-the principal cells of the adaptive immune system-exhibit altered T cell subtype ratios and CD4

Indexed as

Adaptive ImmunityAffectAnimalsBrainCytokinesHumansLymphocytesCytokinesBlood brain barrierCD4(+) T cellsChronic stressCytokinesDepressionIFNγIL-4LymphocytesNeuroimmune

Identifiers

PMID27613155
PMCPMC5339070
OpenAlexW2516757130

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.