Evidence map›Paper›PMID 27611818›Full record

ArticleJournal of veterinary internal medicine2016

Presumptive Iatrogenic Microcystin-Associated Liver Failure and Encephalopathy in a Holsteiner Gelding.

N S Mittelman, J B Engiles, L Murphy, D Vudathala, A L Johnson

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of veterinary internal medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 17 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

N S MittelmanDepartment of Clinical Studies New Bolton Center, University of Pennsylvania New Bolton Center Hospital for Large Animals, Kennett Square, PA. neilmitt@vet.upenn.edu.
J B EngilesPathobiology, University of Pennsylvania School of Veterinary Medicine, Kennett Square, PA.
L MurphyToxicology, University of Pennsylvania New Bolton Center Hospital for Large Animals, Kennett Square, PA.
D VudathalaToxicology, University of Pennsylvania New Bolton Center Hospital for Large Animals, Kennett Square, PA.
A L JohnsonDepartment of Clinical Studies New Bolton Center, University of Pennsylvania, Kennett Square, PA.
American Public Gardens Association · USUniversity of Pennsylvania · USUniversity of Bolton · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An 8-year-old Holsteiner gelding was presented for evaluation of anorexia, obtundation, icterus, and mild colic signs of 48 hours duration. History, physical examination, and initial diagnostics were suggestive of hepatic disease and encephalopathy. Microcystin toxicosis was suspected based on historical administration of a cyanobacteria supplement, associated serum biochemistry abnormalities, and characteristic histopathological changes. Microcystin contamination was confirmed in both supplement containers fed to the horse. Fulminant hepatic failure and encephalopathy progressed resulting in euthanasia. Necropsy findings were consistent with microcystin induced liver failure.

Indexed as

AnimalsBrain DiseasesChemical and Drug Induced Liver InjuryHorse DiseasesHorsesMaleMicrocystinsMicrocystinsBile acidsHorseHyponatremiaLiverNecrosis

Identifiers

PMID27611818
PMCPMC5032859
OpenAlexW2512161775

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.