Evidence map›Paper›PMID 27611346›Full record

ArticleEnvironmental health perspectives2017

Aerobic Fitness and Neurocognitive Function Scores in Young Faroese Adults and Potential Modification by Prenatal Methylmercury Exposure.

Youssef Oulhote, Frodi Debes, Sonja Vestergaard, Pal Weihe, Philippe Grandjean

Open access · diamondAbstract read
In one paragraph

Article in Environmental health perspectives, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
3.9field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

  1. Toxicological evidence that methylmercury exposure amplifies bone destruction and systemic impact associated with apical periodontitis in rats.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2026
    Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 3 countries.

Youssef OulhoteDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.
Frodi Debes
Sonja Vestergaard
Pal Weihe
Philippe Grandjean
Harvard University · USUniversity of the Faroe Islands · FOUniversity of Southern Denmark · DK

Funding

MERCURY-ASSOCIATED NEUROBEHAVIORAL DEFICIT IN CHILDRENU01ES009797 · NIEHS · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI GRANDJEAN, PHILIPPE ADAM · 2000 to 2004
$2.1M
Mercury-Associated Neurobehavioral Deficit in ChildrenR01ES009797 · NIEHS · HARVARD SCHOOL OF PUBLIC HEALTH · PI GRANDJEAN, PHILIPPE ADAM · 2007 to 2011
$2.0M
NIEHS NIH HHS R01 ES009797NIEHS NIH HHS U01 ES009797
6 · The paper itself

Abstract

backgroundExposure to methylmercury was shown to decrease neural stem cell populations, whereas aerobic fitness has beneficial effects on the adult brain that relies on improved neurogenesis in the hippocampus.

objectivesWe examined the association between aerobic fitness and neurocognitive outcomes at young adult age, along with the potential moderating effect of prenatal exposure to methylmercury.

methodsAt age 22 years, 262 members of a Faroese birth cohort, established in 1986-1987, underwent a graded exercise test of aerobic fitness to measure maximal oxygen uptake (VO

resultsA 1 standard deviation (SD) increase in VO

conclusionsHigher aerobic capacity was associated with better performance in short-term memory and processing speed. However, prenatal methylmercury exposure seemed to attenuate these positive associations.

Indexed as

Breath TestsCross-Sectional StudiesDenmarkEnvironmental ExposureEnvironmental PollutantsFemaleFetal BloodHumansMaleMethylmercury CompoundsNeuropsychological TestsSeafoodYoung AdultEnvironmental PollutantsMethylmercury Compounds

Identifiers

PMID27611346
PMCPMC5381980
OpenAlexW2512768509

What OpenQuestion holds

Textmetadata
LicenceCC0
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.