Evidence map›Paper›PMID 27611235›Full record

Trial reportThe International journal of eating disorders2017

Empirically derived personality subtyping for predicting clinical symptoms and treatment response in bulimia nervosa.

Ann F Haynos, Carolyn M Pearson, Linsey M Utzinger, Stephen A Wonderlich, Ross D Crosby, James E Mitchell, Scott J Crow, Carol B Peterson

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in The International journal of eating disorders, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 22 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Emerging Psychological Treatments in Eating Disorders.The Psychiatric clinics of North America · 2019
    Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Ann F HaynosDepartment of Psychiatry, University of Minnesota Medical Center, Minneapolis, Minnesota.
Carolyn M PearsonDepartment of Psychiatry, University of Minnesota Medical Center, Minneapolis, Minnesota.
Linsey M UtzingerDepartment of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, California.
Stephen A WonderlichNeuropsychiatric Research Institute, Fargo, North Dakota.
Ross D CrosbyNeuropsychiatric Research Institute, Fargo, North Dakota.
James E MitchellNeuropsychiatric Research Institute, Fargo, North Dakota.
Scott J CrowDepartment of Psychiatry, University of Minnesota Medical Center, Minneapolis, Minnesota.
Carol B PetersonDepartment of Psychiatry, University of Minnesota Medical Center, Minneapolis, Minnesota.
University of Minnesota Medical Center · USNeuropsychiatric Research Institute · USStanford University · US

Funding

Obesity and Energy Metabolism CoreP30DK050456 · NIDDK · UNIVERSITY OF MINNESOTA TWIN CITIES · PI BERNLOHR, DAVID A · 1995 to 2015
$17.0M
Regional Postdoctoral Training Grant in Eating Disorders ResearchT32MH082761 · NIMH · UNIVERSITY OF MINNESOTA · PI CAROL B. PETERSON · 2009 to 2026
$6.2M
Integrative Cognitive-Affective Therapy for Bulimia NervosaR34MH077571 · NIMH · SANFORD RESEARCH NORTH · PI WONDERLICH, STEPHEN ARTHUR · 2007 to 2009
$590k
NIDDK NIH HHS P30 DK050456NIMH NIH HHS R34 MH077571NIMH NIH HHS T32 MH082761
6 · The paper itself

Abstract

objectiveEvidence suggests that eating disorder subtypes reflecting under-controlled, over-controlled, and low psychopathology personality traits constitute reliable phenotypes that differentiate treatment response. This study is the first to use statistical analyses to identify these subtypes within treatment-seeking individuals with bulimia nervosa (BN) and to use these statistically derived clusters to predict clinical outcomes.

methodsUsing variables from the Dimensional Assessment of Personality Pathology-Basic Questionnaire, K-means cluster analyses identified under-controlled, over-controlled, and low psychopathology subtypes within BN patients (n = 80) enrolled in a treatment trial. Generalized linear models examined the impact of personality subtypes on Eating Disorder Examination global score, binge eating frequency, and purging frequency cross-sectionally at baseline and longitudinally at end of treatment (EOT) and follow-up. In the longitudinal models, secondary analyses were conducted to examine personality subtype as a potential moderator of response to Cognitive Behavioral Therapy-Enhanced (CBT-E) or Integrative Cognitive-Affective Therapy for BN (ICAT-BN).

resultsThere were no baseline clinical differences between groups. In the longitudinal models, personality subtype predicted binge eating (p = 0.03) and purging (p = 0.01) frequency at EOT and binge eating frequency at follow-up (p = 0.045). The over-controlled group demonstrated the best outcomes on these variables. In secondary analyses, there was a treatment by subtype interaction for purging at follow-up (p = 0.04), which indicated a superiority of CBT-E over ICAT-BN for reducing purging among the over-controlled group. DISCUSSION: Empirically derived personality subtyping appears to be a valid classification system with potential to guide eating disorder treatment decisions. © 2016 Wiley Periodicals, Inc.(Int J Eat Disord 2017; 50:506-514).

Indexed as

AdultBulimia NervosaFemaleHumansMalePersonalitySurveys and Questionnairesaffect regulationbulimia nervosaclassificationpersonalitytreatment

Identifiers

PMID27611235
PMCPMC5344779
OpenAlexW2520802395

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.