Evidence map›Paper›PMID 27610561›Full record

ArticleCell2016

Gating Immunity and Death at the Nuclear Pore Complex.

Mary Dasso, Beatriz M A Fontoura

Open access · bronzeAbstract readComment
In one paragraph

Article in Cell, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 3 countries.

Mary DassoDivision of Molecular and Cellular Biology, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA. Electronic address: dassom@mail.nih.gov.
Beatriz M A FontouraDepartment of Cell Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA. Electronic address: beatriz.fontoura@utsouthwestern.edu.
National Institutes of Health · USSouthwestern Medical Center · US

Funding

Mitotic roles of the Nuclear Transport MachineryZIAHD008954 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI DASSO, MARY C. · 2015 to 2025
$25.3M
Splicing and Nuclear Transport of Influenza Virus mRNAR01AI125524 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI COBB, MELANIE H., FONTOURA, BEATRIZ MA · 2016 to 2025
$5.6M
Crosstalk between human mRNA nuclear export and polyadenylation machineriesR01GM113874 · NIGMS · UT SOUTHWESTERN MEDICAL CENTER · PI CONRAD, NICHOLAS K, FONTOURA, BEATRIZ MA · 2015 to 2018
$1.8M
Regulation of Mitotic Kinetochores by the Ran GTPase Z01HD008740 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI DASSO, MARY C. · 2002 to 2008
$1.0M
Chemical intervention of influenza virus RNA nuclear exportR21AI119304 · NIAID · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI FONTOURA, BEATRIZ MA, GARCIA-SASTRE, ADOLFO · 2015 to 2016
$462k
Intramural NIH HHS Z01 HD008740NIAID NIH HHS R01 AI125524NIAID NIH HHS R21 AI119304NIGMS NIH HHS R01 GM113874
6 · The paper itself

Abstract

The nuclear pore complex is the primary conduit for nuclear import and export of molecules. In this issue, Gu et al. uncover a novel mechanism in which immune signaling and programmed cell death require nuclear pore rearrangement and release of sequestered cyclin-dependent kinase inhibitors to elicit immunity and death.

Indexed as

Active Transport, Cell NucleusCell NucleusCyclin-Dependent KinasesHumansNuclear PoreNuclear Pore Complex ProteinsSignal TransductionCyclin-Dependent KinasesNuclear Pore Complex Proteins

Identifiers

PMID27610561
PMCPMC6310161
OpenAlexW2511610690

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.