Evidence map›Paper›PMID 27610365›Full record

ArticleBioMed research international2016

Optimization to the Culture Conditions for Phellinus Production with Regression Analysis and Gene-Set Based Genetic Algorithm.

Zhongwei Li, Yuezhen Xin, Xun Wang, Beibei Sun, Shengyu Xia, Hui Li, Hu Zhu

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BioMed research international, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Zhongwei LiCollege of Computer and Communication Engineering, China University of Petroleum, Qingdao, Shandong 266580, China.
Yuezhen XinCollege of Computer and Communication Engineering, China University of Petroleum, Qingdao, Shandong 266580, China.
Xun WangCollege of Computer and Communication Engineering, China University of Petroleum, Qingdao, Shandong 266580, China; Center for Bioengineering and Biotechnology, China University of Petroleum, Qingdao, Shandong 266580, China.
Beibei SunCollege of Computer and Communication Engineering, China University of Petroleum, Qingdao, Shandong 266580, China.
Shengyu XiaCenter for Bioengineering and Biotechnology, China University of Petroleum, Qingdao, Shandong 266580, China.
Hui LiCenter for Bioengineering and Biotechnology, China University of Petroleum, Qingdao, Shandong 266580, China.
Hu ZhuCenter for Bioengineering and Biotechnology, China University of Petroleum, Qingdao, Shandong 266580, China.ORCID 0000-0002-0478-6392
China University of Petroleum, East China · CN

Funding

Heart Rate Variability and Impulse Control During Alcohol Dependence TreatmentR03AA020925 · NIAAA · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI HOUSTON, REBECCA J · 2012 to 2012
$73k
NIAAA NIH HHS R03 AA020925
6 · The paper itself

Abstract

Phellinus is a kind of fungus and is known as one of the elemental components in drugs to avoid cancers. With the purpose of finding optimized culture conditions for Phellinus production in the laboratory, plenty of experiments focusing on single factor were operated and large scale of experimental data were generated. In this work, we use the data collected from experiments for regression analysis, and then a mathematical model of predicting Phellinus production is achieved. Subsequently, a gene-set based genetic algorithm is developed to optimize the values of parameters involved in culture conditions, including inoculum size, PH value, initial liquid volume, temperature, seed age, fermentation time, and rotation speed. These optimized values of the parameters have accordance with biological experimental results, which indicate that our method has a good predictability for culture conditions optimization.

Indexed as

AlgorithmsBatch Cell Culture TechniquesCulture Media, ConditionedFermentationFungiHydrogen-Ion ConcentrationModels, TheoreticalRegression AnalysisTemperatureCulture Media, Conditioned

Identifiers

PMID27610365
PMCPMC5004040
OpenAlexW2513163670

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.