ArticleF1000Research2016
Results of an attempt to reproduce the STAP phenomenon.
Article in F1000Research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed, 8 citations in OpenAlex.
- Expression of SSEA-4 and Oct-4 from somatic cells in primary mouse gastric cell culture induced by brief strong acid.Molecular and cellular biochemistry · 2021Article
- Postnatal Pluripotent Cells: Quarter of a Century of Research.Bulletin of experimental biology and medicine · 2021Article
- Recent developments in scholarly publishing to improve research practices in the life sciences.Emerging topics in life sciences · 2018Article
- Pluripotent Stem Cells in Adult Tissues: Struggling To Be Acknowledged Over Two Decades.Stem cell reviews and reports · 2017Review
- Irreproducibility of published bioscience research: Diagnosis, pathogenesis and therapy.Molecular metabolism · 2017Article
- Results of an attempt to reproduce the STAP phenomenon.F1000Research · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In 2014, Obokata and colleagues reported their observation of a novel cell reprogramming phenomenon they named 'stimulus-triggered acquisition of pluripotency' (STAP). The most conclusive evidence for the pluripotency of so-called STAP cells was the purported ability of such cells to contribute to chimera formation. Here, I report the results of an attempt by Haruko Obokata to replicate the phenomenon under the supervision of the Scientific Validity Examination Team of RIKEN. In this follow-up study, putative STAP cells prepared by Haruko Obokata were injected into 1051 embryos, of which 591 were recovered. However, the injected cells made no significant contribution in any of the embryos that developed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.