Evidence map›Paper›PMID 27609834›Full record

ArticleJournal of cell science2016

Calsequestrin interacts directly with the cardiac ryanodine receptor luminal domain.

Ahmed Handhle, Chloe E Ormonde, N Lowri Thomas, Catherine Bralesford, Alan J Williams, F Anthony Lai, Spyros Zissimopoulos

Abstract read
In one paragraph

Article in Journal of cell science, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Article
  6. Review
  7. Review
  8. Article
  9. Calsequestrin, a key protein in striated muscle health and disease.Journal of muscle research and cell motility · 2021
    Review
  10. Review
  11. Article
  12. Review
  13. Unbalance Between Sarcoplasmic Reticulum CaFrontiers in physiology · 2019
    Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ahmed HandhleSir Geraint Evans Wales Heart Research Institute, School of Medicine, Cardiff University, Cardiff CF14 4XN, UK.
Chloe E OrmondeSir Geraint Evans Wales Heart Research Institute, School of Medicine, Cardiff University, Cardiff CF14 4XN, UK.
N Lowri ThomasSir Geraint Evans Wales Heart Research Institute, School of Medicine, Cardiff University, Cardiff CF14 4XN, UK.
Catherine BralesfordSir Geraint Evans Wales Heart Research Institute, School of Medicine, Cardiff University, Cardiff CF14 4XN, UK.
Alan J WilliamsSir Geraint Evans Wales Heart Research Institute, School of Medicine, Cardiff University, Cardiff CF14 4XN, UK.
F Anthony LaiSir Geraint Evans Wales Heart Research Institute, School of Medicine, Cardiff University, Cardiff CF14 4XN, UK.
Spyros ZissimopoulosSir Geraint Evans Wales Heart Research Institute, School of Medicine, Cardiff University, Cardiff CF14 4XN, UK zissimopouloss@cardiff.ac.uk.ORCID 0000-0001-5196-9450

Funding

British Heart Foundation FS/08/063British Heart Foundation FS/15/30/31494British Heart Foundation RG/09/009/28069British Heart Foundation RG/15/6/31436
6 · The paper itself

Abstract

Cardiac muscle contraction requires sarcoplasmic reticulum (SR) Ca

Indexed as

CalciumCalsequestrinHEK293 CellsHumansIntracellular SpaceMyocardiumProtein BindingProtein DomainsProtein Interaction MappingProtein Structure, SecondaryRyanodine Receptor Calcium Release ChannelCalciumCalsequestrinRyanodine Receptor Calcium Release ChannelCa2+ intracellular releaseCalsequestrinExcitation-contraction couplingLuminal Ca2+ sensorProtein–protein interactionRyanodine receptorSarcoplasmic reticulum

Identifiers

PMID27609834
PMCPMC5117208

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.