Evidence map›Paper›PMID 27609768›Full record

ArticleAmerican journal of physiology. Gastrointestinal and liver physiology2016

Segmental differences in upregulated apical potassium channels in mammalian colon during potassium adaptation.

Matthew D Perry, Vazhaikkurichi M Rajendran, Kenneth A MacLennan, Geoffrey I Sandle

Open access · hybridAbstract read
In one paragraph

Article in American journal of physiology. Gastrointestinal and liver physiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Ion transport and epithelial barrier dysfunction in experimental models of ulcerative colitis.American journal of physiology. Gastrointestinal and liver physiology · 2025
    Review
  2. Dietary NaCellular and molecular life sciences : CMLS · 2023
    Article
  3. Review
  4. Review
  5. Review
  6. The renal response to potassium stress: integrating past with present.Current opinion in nephrology and hypertension · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Matthew D PerryLeeds Institute of Biomedical and Clinical Sciences, St James's University Hospital, Leeds, United Kingdom.
Vazhaikkurichi M RajendranDepartment of Biochemistry, West Virginia University, Morgantown, West Virginia; and.
Kenneth A MacLennanLeeds Institute of Cancer and Pathology, St James's University Hospital, Leeds, United Kingdom.
Geoffrey I SandleLeeds Institute of Biomedical and Clinical Sciences, St James's University Hospital, Leeds, United Kingdom; g.i.sandle@leeds.ac.uk.
St James's University Hospital · GBWest Virginia University · US

Funding

Role of IK channels in rat distal colonR01DK018777 · NIDDK · YALE UNIVERSITY · PI RAJENDRAN, VAZHAIKKURICHI M. · 1986 to 2010
$2.5M
Role of BK Channels in K+-driven Colonic Water Secretion in Health and DiseaseR01DK104791 · NIDDK · WEST VIRGINIA UNIVERSITY · PI RAJENDRAN, VAZHAIKKURICHI M. · 2015 to 2019
$1.7M
NIDDK NIH HHS R01 DK018777NIDDK NIH HHS R01 DK104791Wellcome Trust
6 · The paper itself

Abstract

Rat proximal and distal colon are net K

Indexed as

AnimalsColonIntestinal MucosaLarge-Conductance Calcium-Activated Potassium ChannelsMalePatch-Clamp TechniquesPotassium, DietaryRatsRats, WistarUp-RegulationLarge-Conductance Calcium-Activated Potassium ChannelsPotassium, DietaryBK channelscolonic K+ adaptationrat colon

Identifiers

PMID27609768
PMCPMC5130553
OpenAlexW2513006232

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.