Evidence map›Paper›PMID 27609706›Full record

ArticleClinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association2017

Dietary Factors Reduce Risk of Acute Pancreatitis in a Large Multiethnic Cohort.

Veronica Wendy Setiawan, Stephen J Pandol, Jacqueline Porcel, Pengxiao C Wei, Lynne R Wilkens, Loïc Le Marchand, Malcolm C Pike, Kristine R Monroe

2 registry-linked trialsOpen access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 23 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 3 pooled it
6.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04761523 narecruitingnot on this mapstarted 2022, after this paper: background citation

The Effect of Dietary Fat Content on the Recurrence of Pancreatitis (EFFORT): Protocol of a Multicentre Randomized Controlled Trial

TypeinterventionalSponsorUniversity of PecsRan2022 to 2026Enrolled384ConditionsAcute PancreatitisArmsDietary intervention: reduced fat diet, Dietary intervention: standard healthy diet
NCT05142657 completednot on this mapstarted 2021, after this paper: background citation

Are There Dietary Factors Affecting the Development of Pancreatitis in Patients With Gallstones?

Typeobservational_patient_registrySponsorIstanbul Training and Research HospitalRan2021 to 2021Enrolled120ConditionsDiet Habit, Gall Stone, PancreatitisArmsdiet survey
3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 3 syntheses or guidelines pooled it, 53 citations in OpenAlex.

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  20. Food-Induced Acute Pancreatitis.Digestive diseases and sciences · 2017
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Veronica Wendy SetiawanDepartment of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California; Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California. Electronic address: vsetiawa@usc.edu.
Stephen J PandolDivision of Gastroenterology, Department of Medicine, Cedars-Sinai Medical Center, and Department of Veterans Affairs, Los Angeles, California.
Jacqueline PorcelNorris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California.
Pengxiao C WeiDepartment of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California.
Lynne R WilkensEpidemiology Program, University of Hawaii Cancer Center, Honolulu, Hawaii.
Loïc Le MarchandEpidemiology Program, University of Hawaii Cancer Center, Honolulu, Hawaii.
Malcolm C PikeDepartment of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California; Memorial Sloan Kettering Cancer Center, New York, New York.
Kristine R MonroeDepartment of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California.
University of Southern California · USCancer Center of Hawaii · USCedars-Sinai Medical Center · USUniversity of Hawaiʻi at Mānoa · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Elisa de Stanchina · 1985 to 2026
$347.4M
University of Hawaii Cancer Center CCSGP30CA071789 · NCI · UNIVERSITY OF HAWAII AT MANOA · PI Xin Chen · 1996 to 2026
$56.2M
The Southernearch Center for ALPD and CirrhosisP50AA011999 · NIAAA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI HIDEKAZU TSUKAMOTO · 1999 to 2026
$45.8M
Understanding Population Differences in Cancer: The MEC StudyU01CA164973 · NCI · UNIVERSITY OF HAWAII AT MANOA · PI HAIMAN, CHRISTOPHER ALAN, LE MARCHAND, LOIC · 2015 to 2025
$37.4M
Understanding Ethnic Differences in Cancer: The Multiethnic Cohort StudyUM1CA164973 · NCI · UNIVERSITY OF HAWAII AT MANOA · PI HENDERSON, BRIAN E, LE MARCHAND, LOIC · 2012 to 2014
$11.3M
Vector and Human Acinar CoreP01DK098108 · NIDDK · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI PANDOL, STEPHEN J. · 2014 to 2018
$8.1M
Targeting diet-induced promotion of Kras-initiated pancreatic adenocarcinomaP01CA163200 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI GUKOVSKAYA, ANNA S. · 2012 to 2016
$6.2M
Pathophysiology, Epidemiology, and Prevention of Pancreatogenic Diabetes - Administrative SupplementU01DK108314 · NIDDK · CEDARS-SINAI MEDICAL CENTER · PI Mark Goodarzi, Stephen J. Pandol · 2015 to 2026
$6.1M
Smoking, Alcohol Abuse and the PancreasI01BX001484 · VA · VA GREATER LOS ANGELES HEALTHCARE SYSTEM · PI PANDOL, STEPHEN J. · 2012 to 2015
–
BLRD VA I01 BX001484NCI NIH HHS P01 CA163200NCI NIH HHS P30 CA008748NCI NIH HHS P30 CA071789NCI NIH HHS U01 CA164973NCI NIH HHS UM1 CA164973NIAAA NIH HHS P50 AA011999NIDDK NIH HHS P01 DK098108NIDDK NIH HHS U01 DK108314
6 · The paper itself

Abstract

BACKGROUND &

aimsPancreatitis is a source of substantial morbidity and health cost in the United States. Little is known about how diet might contribute to its pathogenesis. To characterize dietary factors that are associated with risk of pancreatitis by disease subtype, we conducted a prospective analysis of 145,886 African Americans, Native Hawaiians, Japanese Americans, Latinos, and whites in the Multiethnic Cohort.

methodsIn the Multiethnic Cohort (age at baseline, 45-75 y), we identified cases of pancreatitis using hospitalization claim files from 1993 through 2012. Patients were categorized as having gallstone-related acute pancreatitis (AP) (n = 1210), AP not related to gallstones (n = 1222), or recurrent AP or suspected chronic pancreatitis (n = 378). Diet information was obtained from a questionnaire administered when the study began. Associations were estimated by hazard ratios and 95% confidence intervals using Cox proportional hazard models adjusted for confounders.

resultsDietary intakes of saturated fat (P trend = .0011) and cholesterol (P trend = .0008) and their food sources, including red meat (P trend < .0001) and eggs (P trend = .0052), were associated positively with gallstone-related AP. Fiber intake, however, was associated inversely with gallstone-related AP (P trend = .0005) and AP not related to gallstones (P trend = .0035). Vitamin D, mainly from milk, was associated inversely with gallstone-related AP (P trend = .0015), whereas coffee consumption protected against AP not related to gallstones (P trend < .0001). With the exception of red meat, no other dietary factors were associated with recurrent acute or suspected chronic pancreatitis.

conclusionsAssociations between dietary factors and pancreatitis were observed mainly for gallstone-related AP. Interestingly, dietary fiber protected against AP related and unrelated to gallstones. Coffee drinking protected against AP not associated with gallstones. Further studies are warranted to confirm our findings.

Indexed as

Feeding BehaviorAgedDietFemaleHumansMaleMiddle AgedPancreatitis, Acute NecrotizingProspective StudiesRisk AssessmentSurveys and QuestionnairesUnited StatesEpidemiologyPancreasPopulation

Identifiers

PMID27609706
PMCPMC5241169
OpenAlexW2507511242

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.