Evidence map›Paper›PMID 27609487›Full record

ArticleGut and liver2017

Efficacy of Levofloxacin-Based Third-Line Therapy for the Eradication of

Joo Hyun Lim, Sang Gyun Kim, Ji Hyun Song, Jae Jin Hwang, Dong Ho Lee, Jae Pil Han, Su Jin Hong, Ji Hyun Kim, Seong Woo Jeon, Gwang Ha Kim and 9 more

Open access · diamondAbstract readEvaluation StudyMulticenter Study
In one paragraph

Article in Gut and liver, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 18 citations in OpenAlex.

  1. Guideline
  2. Guideline
  3. Trial
  4. Article
  5. [Approach to Patients with ConsecutiveThe Korean journal of helicobacter and upper gastrointestinal research · 2023
    Review
  6. Treatment of RefractoryGut and liver · 2022
    Review
  7. Trends inFrontiers in medicine · 2022
    Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 14 institutions in 1 country.

Joo Hyun LimDepartment of Internal Medicine, Seoul National University Hospital, Healthcare System Gangnam Center, Healthcare Research Institute, Seoul, Korea.
Sang Gyun KimDepartment of Internal Medicine and Liver Research Institute, Seoul National University College of Medicine, Seoul, Korea.
Ji Hyun SongDepartment of Internal Medicine, Seoul National University Hospital, Healthcare System Gangnam Center, Healthcare Research Institute, Seoul, Korea.
Jae Jin HwangDepartment of Internal Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea.
Dong Ho LeeDepartment of Internal Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea.
Jae Pil HanDepartment of Internal Medicine, Soonchunhyang University College of Medicine, Bucheon, Korea.
Su Jin HongDepartment of Internal Medicine, Soonchunhyang University College of Medicine, Bucheon, Korea.
Ji Hyun KimDepartment of Internal Medicine, Inje University College of Medicine, Busan, Korea.
Seong Woo JeonDepartment of Internal Medicine, Kyungpook National University School of Medicine, Daegu, Korea.
Gwang Ha KimDepartment of Internal Medicine, Pusan National University School of Medicine, Busan, Korea.
Ki-Nam ShimDepartment of Internal Medicine, Ewha Womans University School of Medicine, Seoul, Korea.
Woon Geon ShinDepartment of Internal Medicine, Hallym University College of Medicine, Seoul, Korea.
Tae Ho KimDepartment of Internal Medicine, The Catholic University of Korea College of Medicine, Bucheon, Korea.
Sun Moon KimDepartment of Internal Medicine, Konyang University College of Medicine, Daejeon, Korea.
Il-Kwon ChungDepartment of Internal Medicine, Soonchunhyang University Cheonan Hospital, Soonchunhyang University College of Medicine, Cheonan, Korea.
Hyun-Soo KimDepartment of Internal Medicine, Chonnam National University Medical School, Gwangju, Korea.
Heung Up KimDepartment of Internal Medicine, Jeju National University School of Medicine, Jeju, Korea.
Joongyub LeeMedical Research Collaborating Center, Seoul National University Hospital and Seoul National University College of Medicine, Seoul, Korea.
Jae Gyu KimDepartment of Internal Medicine, Chung-Ang University College of Medicine, Seoul, Korea.
Seoul National University Hospital · KRSoonchunhyang University · KRSeoul National University Bundang Hospital · KRCatholic University of Korea · KRChonnam National University · KRChung-Ang University · KREwha Womans University · KRHallym University · KRInje University · KRJeju National University · KRKonyang University · KRKyungpook National University · KRPusan National University · KRSeoul National University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimsThe resistance rate of

methodsBetween 2002 and 2014, 110 patients in 14 medical centers received levofloxacin-based third-line

resultsThe overall eradiation rate was 71.6%. The adherence rate was 80.0%. All except one received a proton-pump inhibitor, amoxicillin, and levofloxacin. One received a proton-pump inhibitor, amoxicillin, levofloxacin, and clarithromycin, and the eradication was successful. Thirty-one were administered the therapy for 7 days, 25 for 10 days, and 32 for 14 days. No significant differences were observed in the eradication rates between the three groups (7-days, 80.6% vs 10-days, 64.0% vs 14-days, 68.8%, p=0.353). Additionally, no differences were found in the eradiation rates according to the type of peptic ulcer (gastric ulcer, 73.2% vs duodenal/gastroduodenal ulcer, 68.8%, p=0.655).

conclusionsLevofloxacin-based third-line

Indexed as

Helicobacter pyloriAdultAgedAged, 80 and overAnti-Bacterial AgentsDrug Administration ScheduleFemaleHelicobacter InfectionsHumansLevofloxacinMaleMiddle AgedPeptic UlcerRetrospective StudiesTreatment OutcomeYoung AdultAnti-Bacterial AgentsLevofloxacinHelicobacter pyloriLevofloxacinThird-line eradication

Identifiers

PMID27609487
PMCPMC5347646
OpenAlexW2508855145

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.