Evidence map›Paper›PMID 27608937›Full record

ReviewClinical microbiology reviews2016

Microbiome Changes during Tuberculosis and Antituberculous Therapy.

Bo-Young Hong, Nancy Paula Maulén, Alexander J Adami, Hector Granados, María Elvira Balcells, Jorge Cervantes

Open access · bronzeAbstract readReview
In one paragraph

Review in Clinical microbiology reviews, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed, 1 pooled it
5.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 1 synthesis or guideline pooled it, 83 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Observational
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. Status and outlook of pulmonary tuberculosis coinfection.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2025
    Review
  12. The Interplay betweenClinics and practice · 2024
    Review
  13. Review
  14. Article
  15. Article
  16. Indian journal of microbiology · 2022
    Article
  17. Article
  18. Review
  19. Journal of personalized medicine · 2022
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 2 countries.

Bo-Young HongThe Jackson Laboratory for Genomic Medicine, Farmington, Connecticut, USA.
Nancy Paula MaulénLaboratorio Clinico, Hospital Felix Bulnes Cerda, Santiago, Chile.
Alexander J AdamiDepartment of Immunology, University of Connecticut Health, Farmington, Connecticut, USA.
Hector GranadosDepartment of Pediatrics, Division of Endocrinology, Texas Tech University Health Sciences Center, El Paso, Texas, USA.
María Elvira BalcellsDepartamento de Enfermedades Infecciosas, Escuela de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile.
Jorge CervantesPaul L. Foster School of Medicine, Texas Tech University Health Sciences Center, El Paso, Texas, USA jorge.cervantes@ttuhsc.edu.
Jackson Laboratory · USPontificia Universidad Católica de Chile · CLTexas Tech University · USTexas Tech University Health Sciences Center · USUConn Health · US

Funding

Role of the Microbiome in Regulating House Dust Mite-Induced AsthmaF30HL126324 · NHLBI · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI ADAMI, ALEXANDER JOHN · 2015 to 2018
$168k
NHLBI NIH HHS F30 HL126324
6 · The paper itself

Abstract

The critical role of commensal microbiota in the human body has been increasingly recognized, and our understanding of its implications in human health and disease has expanded rapidly. The lower respiratory tract contains diverse communities of microbes known as lung microbiota, which are present in healthy individuals and in individuals with respiratory diseases. The dysbiosis of the airway microbiota in pulmonary tuberculosis (TB) may play a role in the pathophysiological processes associated with TB disease. Recent studies of the lung microbiome have pointed out changes in lung microbial communities associated with TB and other lung diseases and have also begun to elucidate the profound effects that antituberculous drug therapy can have on the human lung microbiome composition. In this review, the potential role of the human microbiome in TB pathogenesis and the changes in the human microbiome with Mycobacterium tuberculosis infection and TB therapy are presented and discussed.

Indexed as

Antitubercular AgentsDysbiosisHumansMicrobiotaRespiratory SystemTuberculosisAntitubercular Agents

Identifiers

PMID27608937
PMCPMC5010754
OpenAlexW2516549405

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.