Evidence map›Paper›PMID 27608810›Full record

ArticleThe international journal of neuropsychopharmacology2016

Marmoset Serotonin 5-HT1A Receptor Mapping with a Biased Agonist PET Probe 18F-F13714: Comparison with an Antagonist Tracer 18F-MPPF in Awake and Anesthetized States.

Chihiro Yokoyama, Aya Mawatari, Akihiro Kawasaki, Chiho Takeda, Kayo Onoe, Hisashi Doi, Adrian Newman-Tancredi, Luc Zimmer, Hirotaka Onoe

Open access · goldAbstract readComparative Study
In one paragraph

Article in The international journal of neuropsychopharmacology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
  2. Radiotracers for the Central Serotoninergic System.Pharmaceuticals (Basel, Switzerland) · 2022
    Review
  3. [Frontiers in neuroscience · 2021
    Article
  4. Type of Anaesthetic Influences [Molecular imaging and biology · 2020
    Article
  5. The selective 5-HTNeuropharmacology · 2020
    Article
  6. Review
  7. Review
  8. Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Chihiro YokoyamaRIKEN Center for Life Science Technologies, Kobe, Hyogo, Japan (Dr Yokoyama, Ms Mawatari, Mr Kawasaki, Ms Takeda, Ms K. Onoe, Dr Doi, Dr H. Onoe); Neurolixis Inc, Dana Point, CA (Dr Newman-Tancredi); Université Claude Bernard Lyon 1, Hospices Civils de Lyon, INSERM, CNRS, Lyon Neuroscience Research Center, Lyon, France (Dr Zimmer).
Aya MawatariRIKEN Center for Life Science Technologies, Kobe, Hyogo, Japan (Dr Yokoyama, Ms Mawatari, Mr Kawasaki, Ms Takeda, Ms K. Onoe, Dr Doi, Dr H. Onoe); Neurolixis Inc, Dana Point, CA (Dr Newman-Tancredi); Université Claude Bernard Lyon 1, Hospices Civils de Lyon, INSERM, CNRS, Lyon Neuroscience Research Center, Lyon, France (Dr Zimmer).
Akihiro KawasakiRIKEN Center for Life Science Technologies, Kobe, Hyogo, Japan (Dr Yokoyama, Ms Mawatari, Mr Kawasaki, Ms Takeda, Ms K. Onoe, Dr Doi, Dr H. Onoe); Neurolixis Inc, Dana Point, CA (Dr Newman-Tancredi); Université Claude Bernard Lyon 1, Hospices Civils de Lyon, INSERM, CNRS, Lyon Neuroscience Research Center, Lyon, France (Dr Zimmer).
Chiho TakedaRIKEN Center for Life Science Technologies, Kobe, Hyogo, Japan (Dr Yokoyama, Ms Mawatari, Mr Kawasaki, Ms Takeda, Ms K. Onoe, Dr Doi, Dr H. Onoe); Neurolixis Inc, Dana Point, CA (Dr Newman-Tancredi); Université Claude Bernard Lyon 1, Hospices Civils de Lyon, INSERM, CNRS, Lyon Neuroscience Research Center, Lyon, France (Dr Zimmer).
Kayo OnoeRIKEN Center for Life Science Technologies, Kobe, Hyogo, Japan (Dr Yokoyama, Ms Mawatari, Mr Kawasaki, Ms Takeda, Ms K. Onoe, Dr Doi, Dr H. Onoe); Neurolixis Inc, Dana Point, CA (Dr Newman-Tancredi); Université Claude Bernard Lyon 1, Hospices Civils de Lyon, INSERM, CNRS, Lyon Neuroscience Research Center, Lyon, France (Dr Zimmer).
Hisashi DoiRIKEN Center for Life Science Technologies, Kobe, Hyogo, Japan (Dr Yokoyama, Ms Mawatari, Mr Kawasaki, Ms Takeda, Ms K. Onoe, Dr Doi, Dr H. Onoe); Neurolixis Inc, Dana Point, CA (Dr Newman-Tancredi); Université Claude Bernard Lyon 1, Hospices Civils de Lyon, INSERM, CNRS, Lyon Neuroscience Research Center, Lyon, France (Dr Zimmer).
Adrian Newman-TancrediRIKEN Center for Life Science Technologies, Kobe, Hyogo, Japan (Dr Yokoyama, Ms Mawatari, Mr Kawasaki, Ms Takeda, Ms K. Onoe, Dr Doi, Dr H. Onoe); Neurolixis Inc, Dana Point, CA (Dr Newman-Tancredi); Université Claude Bernard Lyon 1, Hospices Civils de Lyon, INSERM, CNRS, Lyon Neuroscience Research Center, Lyon, France (Dr Zimmer).
Luc ZimmerRIKEN Center for Life Science Technologies, Kobe, Hyogo, Japan (Dr Yokoyama, Ms Mawatari, Mr Kawasaki, Ms Takeda, Ms K. Onoe, Dr Doi, Dr H. Onoe); Neurolixis Inc, Dana Point, CA (Dr Newman-Tancredi); Université Claude Bernard Lyon 1, Hospices Civils de Lyon, INSERM, CNRS, Lyon Neuroscience Research Center, Lyon, France (Dr Zimmer).
Hirotaka OnoeRIKEN Center for Life Science Technologies, Kobe, Hyogo, Japan (Dr Yokoyama, Ms Mawatari, Mr Kawasaki, Ms Takeda, Ms K. Onoe, Dr Doi, Dr H. Onoe); Neurolixis Inc, Dana Point, CA (Dr Newman-Tancredi); Université Claude Bernard Lyon 1, Hospices Civils de Lyon, INSERM, CNRS, Lyon Neuroscience Research Center, Lyon, France (Dr Zimmer). hiro.onoe@riken.jp.
Neurolixis (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn vivo mapping by positron emission tomography of the serotonin 1A receptors has been hindered by the lack of suitable agonist positron emission tomography probes.

methodsPositron emission tomography scans were conducted in a cohort of common marmosets (n=4) using the serotonin 1A receptor biased agonist radiotracer,

results

conclusionsThese findings highlight the importance of investigating the brain imaging of serotonin 1A receptors using agonist probes such as

Indexed as

Anesthesia, GeneralConsciousnessPositron-Emission TomographyAminopyridinesAnimalsBrainCallithrixFluorine RadioisotopesMaleMolecular ImagingPiperazinesPiperidinesPredictive Value of TestsProtein BindingPyridinesRadiopharmaceuticals3-chloro-4-fluorophenyl-(4-fluoro-4-(((5-methyl-6-methylaminopyridin-2-ylmethyl)amino)methyl)piperidin-1-yl)methanone4-(2'-methoxyphenyl)-1-(2'-(N-2'-pyridinyl)-p-(18F)fluorobenzamido )ethylpiperazineAminopyridinesFluorine RadioisotopesPiperazinesPiperidinesPyridinesRadiopharmaceuticalsReceptor, Serotonin, 5-HT1ASerotonin 5-HT1 Receptor Agonists5-hydroxytryptaminebiased agonismCallithrix jacchusF13714

Identifiers

PMID27608810
PMCPMC5203761
OpenAlexW2512483042

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.