Evidence map›Paper›PMID 27608045›Full record

ReviewDiagnostics (Basel, Switzerland)2016

Dynamic Contrast-Enhanced CT in Patients with Pancreatic Cancer.

Rie Ø Eriksen, Louise S Strauch, Michael Sandgaard, Thomas S Kristensen, Michael B Nielsen, Carsten A Lauridsen

Open access · goldAbstract readReview
In one paragraph

Review in Diagnostics (Basel, Switzerland), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Fibrotic Response to Neoadjuvant Therapy Predicts Survival in Pancreatic Cancer and Is Measurable with Collagen-Targeted Molecular MRI.Clinical cancer research : an official journal of the American Association for Cancer Research · 2020
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Rie Ø EriksenDepartment of Diagnostic Radiology, Rigshospitalet, Copenhagen University Hospital, DK-2100 Copenhagen, Denmark. roestbjerge@gmail.com.
Louise S StrauchDepartment of Diagnostic Radiology, Rigshospitalet, Copenhagen University Hospital, DK-2100 Copenhagen, Denmark. louisesoeborg9@gmail.com.
Michael SandgaardDepartment of Diagnostic Radiology, Rigshospitalet, Copenhagen University Hospital, DK-2100 Copenhagen, Denmark. michael@sandgaard.org.
Thomas S KristensenDepartment of Diagnostic Radiology, Rigshospitalet, Copenhagen University Hospital, DK-2100 Copenhagen, Denmark. tskaarup@yahoo.com.
Michael B NielsenDepartment of Diagnostic Radiology, Rigshospitalet, Copenhagen University Hospital, DK-2100 Copenhagen, Denmark. mbn@dadlnet.dk.
Carsten A LauridsenDepartment of Diagnostic Radiology, Rigshospitalet, Copenhagen University Hospital, DK-2100 Copenhagen, Denmark. Cala@phmetropol.dk.
Copenhagen University Hospital · DKMetropolitan University College · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this systematic review is to provide an overview of the use of Dynamic Contrast-enhanced Computed Tomography (DCE-CT) in patients with pancreatic cancer. This study was composed according to the PRISMA guidelines 2009. The literature search was conducted in PubMed, Cochrane Library, EMBASE, and Web of Science databases to identify all relevant publications. The QUADAS-2 tool was implemented to assess the risk of bias and applicability concerns of each included study. The initial literature search yielded 483 publications. Thirteen articles were included. Articles were categorized into three groups: nine articles concerning primary diagnosis or staging, one article about tumor response to treatment, and three articles regarding scan techniques. In exocrine pancreatic tumors, measurements of blood flow in eight studies and blood volume in seven studies were significantly lower in tumor tissue, compared with measurements in pancreatic tissue outside of tumor, or normal pancreatic tissue in control groups of healthy volunteers. The studies were heterogeneous in the number of patients enrolled and scan protocols. Perfusion parameters measured and analyzed by DCE-CT might be useful in the investigation of characteristic vascular patterns of exocrine pancreatic tumors. Further clinical studies are desired for investigating the potential of DCE-CT in pancreatic tumors.

Indexed as

DCE-CTdiagnosticspancreatic cancerscan techniquestreatment response

Identifiers

PMID27608045
PMCPMC5039568
OpenAlexW2516203425

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.