Evidence map›Paper›PMID 27607553›Full record

ReviewAnnual review of microbiology2016

Evolution and Ecology of Actinobacteria and Their Bioenergy Applications.

Gina R Lewin, Camila Carlos, Marc G Chevrette, Heidi A Horn, Bradon R McDonald, Robert J Stankey, Brian G Fox, Cameron R Currie

Abstract readReview
In one paragraph

Review in Annual review of microbiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 154 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
154citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

154 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Molecules (Basel, Switzerland) · 2020
    Pooled it
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  11. Whole-genomic and transcriptomic analyses elucidateApplied and environmental microbiology · 2026
    Article
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  13. The bacteria of a fig community.Microbiology spectrum · 2026
    Article
  14. Article
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  20. Article

94 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Gina R LewinDepartment of Bacteriology, University of Wisconsin-Madison, Wisconsin 53706; email: currie@bact.wisc.edu.
Camila CarlosDepartment of Bacteriology, University of Wisconsin-Madison, Wisconsin 53706; email: currie@bact.wisc.edu.
Marc G ChevretteDepartment of Bacteriology, University of Wisconsin-Madison, Wisconsin 53706; email: currie@bact.wisc.edu.
Heidi A HornDepartment of Bacteriology, University of Wisconsin-Madison, Wisconsin 53706; email: currie@bact.wisc.edu.
Bradon R McDonaldDepartment of Bacteriology, University of Wisconsin-Madison, Wisconsin 53706; email: currie@bact.wisc.edu.
Robert J StankeyDepartment of Bacteriology, University of Wisconsin-Madison, Wisconsin 53706; email: currie@bact.wisc.edu.
Brian G FoxDepartment of Energy Great Lakes Bioenergy Research Center, University of Wisconsin-Madison, Wisconsin 53726.
Cameron R CurrieDepartment of Bacteriology, University of Wisconsin-Madison, Wisconsin 53706; email: currie@bact.wisc.edu.

Funding

GRADUATE TRAINING IN MOLECULAR BIOSCIENCEST32GM007215 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI HULL, CHRISTINA M · 1985 to 2018
$22.5M
Metabolomics driven discovery of drug leads from symbiotic bacteriaU19AI109673 · NIAID · UNIVERSITY OF WISCONSIN-MADISON · PI ANDES, DAVID R, CURRIE, CAMERON ROBERT · 2014 to 2018
$16.2M
Chemistry-Biology Interface Training ProgramT32GM008505 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI BLACKWELL, HELEN E. · 1993 to 2023
$9.8M
Novel therapeutic agents from the bacterial symbionts of Brazilian invertebratesU19TW009872 · FIC · HARVARD MEDICAL SCHOOL · PI CLARDY, JON, PUPO, MONICA T · 2014 to 2018
$4.4M
FIC NIH HHS U19 TW009872NIAID NIH HHS U19 AI109673NIGMS NIH HHS T32 GM007215NIGMS NIH HHS T32 GM008505
6 · The paper itself

Abstract

The ancient phylum Actinobacteria is composed of phylogenetically and physiologically diverse bacteria that help Earth's ecosystems function. As free-living organisms and symbionts of herbivorous animals, Actinobacteria contribute to the global carbon cycle through the breakdown of plant biomass. In addition, they mediate community dynamics as producers of small molecules with diverse biological activities. Together, the evolution of high cellulolytic ability and diverse chemistry, shaped by their ecological roles in nature, make Actinobacteria a promising group for the bioenergy industry. Specifically, their enzymes can contribute to industrial-scale breakdown of cellulosic plant biomass into simple sugars that can then be converted into biofuels. Furthermore, harnessing their ability to biosynthesize a range of small molecules has potential for the production of specialty biofuels.

Indexed as

BiotechnologyActinobacteriaBiodiversityBiofuelsBiological EvolutionBiofuelsactinomycetesbiofuelsbiotechnologycellulasesStreptomycessymbiosis

Identifiers

PMID27607553
PMCPMC5703056

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.