ArticleMedical principles and practice : international journal of the Kuwait University, Health Science Centre2017
Factors Affecting Adherence to Statins in Hypercholesterolemic Kuwaiti Patients: A Cross-Sectional Study.
Article in Medical principles and practice : international journal of the Kuwait University, Health Science Centre, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Systematic review of the predictors of statin adherence for the primary prevention of cardiovascular disease.PloS one · 2019Pooled it
- Determinants of Medication Non-Adherence in 1,750 Indonesian Adults with Chronic Diseases: A Nationwide Cross-Sectional Study.Patient preference and adherence · 2026Article
- Level of medication non-adherence among ambulatory patients with dyslipidemia and comorbid illness in Northwest Ethiopia: a multicenter cross-sectional study.Therapeutic advances in chronic disease · 2025Article
- Prevalence and associated factors of non-adherence to antihyperlipidemic medication: a nationwide cross sectional survey in Pakistan.Scientific reports · 2024Article
- Adherence to Statin Among Diabetic Patients in Diabetic Centers in Qassim Region, Saudi Arabia.Cureus · 2023Article
- Medication Discussions With Patients With Cardiovascular Disease in the Emergency Department: An Opportunity for Emergency Nurses to Engage Patients to Support Medication Reconciliation.Journal of emergency nursing · 2023Observational
- Single-Pill Combination to Improve Hypertension Treatment: Pharmaceutical Industry Development.International journal of environmental research and public health · 2022Review
- Factors Associated with Non-Adherence to Drugs in Patients with Chronic Diseases Who Go to Pharmacies in Spain.International journal of environmental research and public health · 2021Observational
- Identifying adherent patients to newly initiated statins using previous adherence to chronic medications.Journal of managed care & specialty pharmacy · 2021Article
- Determinants of Non-Adherence to the Medications for Dyslipidemia: A Systematic Review.Patient preference and adherence · 2021Review
- Validation of self-reported adherence in chronic patients visiting pharmacies and factors associated with the overestimation and underestimation of good adherence.European journal of clinical pharmacology · 2020Observational
- Patient Compliance: Fact or Fiction?Innovations in pharmacy · 2019Article
- Medication adherence in chronic illness: do beliefs about medications play a role?Patient preference and adherence · 2018Article
- Improving Medication Adherence in Coronary Heart Disease.Current cardiology reports · 2017Review
- Assessment of Medication Adherence in Patients with Chronic Diseases in Tabuk, Kingdom of Saudi Arabia.Journal of research in pharmacy practiceArticle
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2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThis study examined statin adherence amongst Kuwaiti hypercholesterolemic patients in order to identify factors associated with poor adherence and to determine whether or not an association exists between statin adherence and the risk profile of coronary heart disease (CHD). SUBJECTS AND
methodsTwo hundred hypercholesterolemic patients (30-69 years of age) were recruited from Kuwaiti primary healthcare clinics and interviewed about demographic characteristics, pre-existing self-reported medical conditions and prescribed medications. The Morisky Medication Adherence Scale was used to assess statin adherence (a self-reported, medication-adherence questionnaire divided into 3 levels, with a score of 8 denoting high adherence, 6 to <8 denoting medium adherence and <6 denoting low adherence). Data regarding anthropometric, psychological and serum risk factors were collected using 2 additional questionnaires, laboratory tests and bioelectrical impedance scales. Binary logistic regression was used to determine predictors of adherence and general linear modelling was used to test relationships between continuous outcomes and statin adherence.
resultsOf the 200 participants, 117 (58.5%) reported low adherence, 83 (41.5%) reported medium adherence and no patients (0%) scored high adherence. Younger patients (aged 30-50 years) had lower adherence than older patients (>50 years) [odds ratio (OR) 1.05; 95% confidence interval (CI) 1.01-1.09] for every extra year; p < 0.01). Those without diabetes, i.e. 113 (56.5%), were less likely to report medium adherence than those with diabetes (OR 0.42; 95% CI 0.23-0.75; p < 0.01). Low statin adherence was associated with higher levels of plasma cholesterol (p < 0.001) and low-density lipoprotein (p < 0.01).
conclusionIn this study, there was a high prevalence of low statin adherence, especially among younger patients with fewer concomitant diseases. The results indicated an inverse relationship between statin adherence and CHD risk profile.
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