Evidence map›Paper›PMID 27606068›Full record

ArticleMaterials research express2016

Sodium hydroxide catalyzed monodispersed high surface area silica nanoparticles.

Snehasis Bhakta, Chandra K Dixit, Itti Bist, Karim Abdel Jalil, Steven L Suib, James F Rusling

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In one paragraph

Article in Materials research express, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Snehasis BhaktaDepartment of Chemistry, University of Connecticut, Storrs, CT 06269-3060, USA.
Chandra K DixitDepartment of Chemistry, University of Connecticut, Storrs, CT 06269-3060, USA.
Itti BistDepartment of Chemistry, University of Connecticut, Storrs, CT 06269-3060, USA.
Karim Abdel JalilDepartment of Chemistry, University of Connecticut, Storrs, CT 06269-3060, USA.
Steven L SuibDepartment of Chemistry, University of Connecticut, Storrs, CT 06269-3060, USA; Institute of Materials Science, University of Connecticut, Storrs, CT 06269-3136, USA.
James F RuslingDepartment of Chemistry, University of Connecticut, Storrs, CT 06269-3060, USA; Institute of Materials Science, University of Connecticut, Storrs, CT 06269-3136, USA; Department of Cell Biology, University of Connecticut Health Center, Farmington, CT 06030, USA; School of Chemistry, National University of Ireland at Galway, Galway, Ireland.

Funding

Protein Biomarker Arrays for Personalized Treatment of Prostate CancerR01EB016707 · NIBIB · UNIVERSITY OF CONNECTICUT STORRS · PI RUSLING, JAMES F. · 2014 to 2017
$1.4M
Protein Biosensor Arrays Based on NanomaterialsR01EB014586 · NIBIB · UNIVERSITY OF CONNECTICUT STORRS · PI RUSLING, JAMES F. · 2011 to 2014
$1.4M
NIBIB NIH HHS R01 EB014586NIBIB NIH HHS R01 EB016707
6 · The paper itself

Abstract

Understanding of the synthesis kinetics and our ability to modulate medium conditions allowed us to generate nanoparticles via an ultra-fast process. The synthesis medium is kept quite simple with tetraethyl orthosilicate (TEOS) as precursor and 50% ethanol and sodium hydroxide catalyst. Synthesis is performed under gentle conditions at 20 °C for 20 min Long synthesis time and catalyst-associated drawbacks are most crucial in silica nanoparticle synthesis. We have addressed both these bottlenecks by replacing the conventional Stober catalyst, ammonium hydroxide, with sodium hydroxide. We have reduced the overall synthesis time from 20 to 1/3 h, ~60-fold decrease, and obtained highly monodispersed nanoparticles with 5-fold higher surface area than Stober particles. We have demonstrated that the developed NPs with ~3-fold higher silane can be used as efficient probes for biosensor applications.

Indexed as

high surface areasilanizationsilica nanoparticlesodium hydroxideStober

Identifiers

PMID27606068
PMCPMC5010867

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.