Evidence map›Paper›PMID 27605969›Full record

Trial reportAfrican health sciences2016

Weight loss improves biomarkers endothelial function and systemic inflammation in obese postmenopausal Saudi women.

Shehab Mahmoud Abd El-Kader, Mohammed H Saiem Al-Dahr

Open access · diamondAbstract readComparative StudyRandomized Controlled Trial
In one paragraph

Trial report in African health sciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 3 pooled it
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 3 syntheses or guidelines pooled it, 23 citations in OpenAlex.

  1. Guideline
  2. Prevalence, risk factors, and interventions for obesity in Saudi Arabia: A systematic review.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2022
    Pooled it
  3. Pooled it
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Shehab Mahmoud Abd El-KaderDepartment of Physical Therapy, Faculty of Applied Medical Sciences, King Abdulaziz University.
Mohammed H Saiem Al-DahrDepartment of Medical Laboratory Technology, Faculty of Applied Medical Sciences, King Abdulaziz University.
King Abdulaziz University · SAKing Saud bin Abdulaziz University for Health Sciences · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlthough postmenopausal associated disorders are important public health problems worldwide, to date limited studies evaluated the endothelial function and systemic inflammation response to weight loss in obese postmenopausal women.

objectiveThis study was done to evaluate the endothelial function and systemic inflammation response to weight loss in obese postmenopausal Saudi women. MATERIAL AND

methodsEighty postmenopausal obese Saudi women (mean age 52.64±6.13 year) participated in two groups: Group (A) received aerobic exercise on treadmill and diet whereas, group (B) received no intervention. Markers of inflammation and endothelial function were measured before and after 3 months at the end of the study.

resultsThe values of body mass index(BMI), interleukin-6 (IL-6), tumor necrosis factor-alpha (TNF-α), C-reactive protein (CRP), inter-cellular adhesion molecule (ICAM-1), vascular cell adhesion molecule (VCAM-1) and plasminogen activator inhibitor-1 activity (PAI-1:Ac) were significantly decreased in group (A), while changes were not significant in group (B). Also, there were significant differences between mean levels of the investigated parameters in group (A) and group (B) after treatment.

conclusionWeight loss ameliorates inflammatory cytokines and markers of endothelial function in obese postmenopausal Saudi women.

Indexed as

Weight LossAnthropometryBiomarkersBody Mass IndexCytokinesDeveloping CountriesDiet, ReducingEndotheliumEnzyme-Linked Immunosorbent AssayExerciseFemaleHumansMiddle AgedObesityPostmenopauseReference ValuesBiomarkersCytokinescytokinesdietendothelial functionexerciseMenopause

Identifiers

PMID27605969
PMCPMC4994544
OpenAlexW2472024485

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.