Evidence map›Paper›PMID 27605935›Full record

ArticleJournal of geriatric cardiology : JGC2016

Cognitive function and adherence to anticoagulation treatment in patients with atrial fibrillation.

Beata Jankowska-Polańska, Lomper Katarzyna, Alberska Lidia, Jaroch Joanna, Krzysztof Dudek, Uchmanowicz Izabella

Abstract read
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In one paragraph

Article in Journal of geriatric cardiology : JGC, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Cognitive function and telemedicine-based, village doctor-led care for atrial fibrillation.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2026
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  18. Canadian family physician Medecin de famille canadien · 2018
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Beata Jankowska-PolańskaDepartment of Clinical Nursing, Wrocław Medical University, Bartla, Wroclaw, Poland.
Lomper KatarzynaDepartment of Clinical Nursing, Wrocław Medical University, Bartla, Wroclaw, Poland.
Alberska LidiaEmergency Medicine Centre, Anesthesiology Unit, Marciniak Lower-Silesian Specialist Hospital, Fieldorfa, Wrocław, Poland.
Jaroch JoannaEmergency Medicine Centre, Cardiology Unit, Marciniak Lower-Silesian Specialist Hospital, Fieldorfa, Wrocław, Poland.
Krzysztof DudekDepartment of Logistic and Transport Systems, University of Technology, Wybrzeże Stanisława Wyspiańskiego, Wrocław, Poland.
Uchmanowicz IzabellaDepartment of Clinical Nursing, Wrocław Medical University, Bartla, Wroclaw, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMedication adherence is an integral part of the comprehensive care of patients with atrial fibrillation (AF) receiving oral anticoagulations (OACs) therapy. Many patients with AF are elderly and may suffer from some form of cognitive impairment. This study was conducted to investigate whether cognitive impairment affects the level of adherence to anticoagulation treatment in AF patients.

methodsThe study involved 111 AF patients (mean age, 73.5 ± 8.3 years) treated with OACs. Cognitive function was assessed using the Mini Mental State Examination (MMSE). The level of adherence was assessed by the 8-item Morisky Medication Adherence Scale (MMAS-8). Scores on the MMAS-8 range from 0 to 8, with scores < 6 reflecting low adherence, 6 to < 8 medium adherence, and 8 high adherence.

results46.9% of AF patients had low adherence, 18.8% had moderate adherence, and 33.3% had high adherence to OACs. Patients with lower adherence were older than those with moderate or high adherence (76.6 ± 8.7 vs. 71.3 ± 6.4 vs. 71.1 ± 6.7 years) and obtained low MMSE scores, indicating cognitive disorders or dementia (MMSE = 22.3 ± 4.2). Patients with moderate or high adherence obtained high MMSE test results (27.5 ± 1.7 and 27.5 ± 3.6). According to Spearman's rank correlation, worse adherence to treatment with OACs was determined by older age (rS = -0.372) and lower MMSE scores (rS = 0.717). According to multivariate regression analysis, the level of cognitive function was a significant independent predictor of adherence (b = 1.139).

conclusionsCognitive impairment is an independent determinant of compliance with pharmacological therapy in elderly patients with AF. Lower adherence, beyond the assessment of cognitive function, is related to the age of patients.

Indexed as

Anticoagulation treatmentAtrial fibrillationCognitive impairmentMedication adherence

Identifiers

PMID27605935
PMCPMC4996829

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.