Evidence map›Paper›PMID 27605536›Full record

ArticleJournal of neurophysiology2016

L-type calcium channels refine the neural population code of sound level.

Calum Alex Grimsley, David Brian Green, Shobhana Sivaramakrishnan

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of neurophysiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Calum Alex GrimsleyDepartment of Anatomy and Neurobiology, Northeast Ohio Medical University, Rootstown, Ohio.
David Brian GreenDepartment of Anatomy and Neurobiology, Northeast Ohio Medical University, Rootstown, Ohio.
Shobhana SivaramakrishnanDepartment of Anatomy and Neurobiology, Northeast Ohio Medical University, Rootstown, Ohio ssivaram@neomed.edu.
Northeast Ohio Medical University · US

Funding

Regulation of excitability in a sensory system by cellular and network componentsR01DC008120 · NIDCD · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI SIVARAMAKRISHNAN, SHOBHANA · 2006 to 2010
$1.6M
ARRA NIH HHSNIDCD NIH HHS R01 DC008120
6 · The paper itself

Abstract

The coding of sound level by ensembles of neurons improves the accuracy with which listeners identify how loud a sound is. In the auditory system, the rate at which neurons fire in response to changes in sound level is shaped by local networks. Voltage-gated conductances alter local output by regulating neuronal firing, but their role in modulating responses to sound level is unclear. We tested the effects of L-type calcium channels (Ca

Indexed as

Sound4-AminopyridineAcoustic StimulationAction PotentialsAmifampridineAnimalsBiophysical PhenomenaCalciumCalcium Channel BlockersCalcium Channels, L-TypeExcitatory Amino Acid AntagonistsInferior ColliculiIn Vitro TechniquesMiceMice, Inbred CBANeurons2,3-dioxo-6-nitro-7-sulfamoylbenzo(f)quinoxaline4-AminopyridineAmifampridineCalciumCalcium Channel BlockersCalcium Channels, L-TypeExcitatory Amino Acid AntagonistsNimodipineomega-Conotoxin GVIAPotassium Channel BlockersQuinoxalinesauditory midbraindynamic rangeinferior colliculuslevel tuninglocal circuitsrate-level functions

Identifiers

PMID27605536
PMCPMC5133292
OpenAlexW2511651329

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.