ArticleJournal of neurophysiology2016
Normal correspondence of tectal maps for saccadic eye movements in strabismus.
Article in Journal of neurophysiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 15 citations in OpenAlex.
- Retinal Input to Macaque Superior Colliculus Derives from Branching Axons Projecting to the Lateral Geniculate Nucleus.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Microstimulation of Interstitial Nucleus of Cajal Evokes Directionally Disconjugate Eye Movements in Monkeys With Pattern Strabismus.Investigative ophthalmology & visual science · 2022Article
- Fixation eye movement abnormalities and stereopsis recovery following strabismus repair.Scientific reports · 2021Article
- Abnormal Tuning in Nucleus Prepositus Hypoglossi of Monkeys With "A" Pattern Exotropia.Investigative ophthalmology & visual science · 2020Article
- Response Properties of Cells Within the Rostral Superior Colliculus of Strabismic Monkeys.Investigative ophthalmology & visual science · 2019Article
- Abnormal Eye Position Signals in Interstitial Nucleus of Cajal in Monkeys With "A" Pattern Strabismus.Investigative ophthalmology & visual science · 2019Article
- Spontaneous Reattachment of the Medial Rectus After Free Tenotomy.Journal of pediatric ophthalmology and strabismus · 2018Article
- Normal Topography and Binocularity of the Superior Colliculus in Strabismus.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2018Article
- Nonhuman Primate Studies to Advance Vision Science and Prevent Blindness.ILAR journal · 2017Review
- Neural mechanisms of oculomotor abnormalities in the infantile strabismus syndrome.Journal of neurophysiology · 2017Review
- Electrical stimulation of superior colliculus affects strabismus angle in monkey models for strabismus.Journal of neurophysiology · 2017Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
Abstract
The superior colliculus is a major brain stem structure for the production of saccadic eye movements. Electrical stimulation at any given point in the motor map generates saccades of defined amplitude and direction. It is unknown how this saccade map is affected by strabismus. Three macaques were raised with exotropia, an outwards ocular deviation, by detaching the medial rectus tendon in each eye at age 1 mo. The animals were able to make saccades to targets with either eye and appeared to alternate fixation freely. To probe the organization of the superior colliculus, microstimulation was applied at multiple sites, with the animals either free-viewing or fixating a target. On average, microstimulation drove nearly conjugate saccades, similar in both amplitude and direction but separated by the ocular deviation. Two monkeys showed a pattern deviation, characterized by a systematic change in the relative position of the two eyes with certain changes in gaze angle. These animals' saccades were slightly different for the right eye and left eye in their amplitude or direction. The differences were consistent with the animals' underlying pattern deviation, measured during static fixation and smooth pursuit. The tectal map for saccade generation appears to be normal in strabismus, but saccades may be affected by changes in the strabismic deviation that occur with different gaze angles.
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Registered trials
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