Evidence map›Paper›PMID 27605533›Full record

ArticleJournal of neurophysiology2016

Entanglement between thermoregulation and nociception in the rat: the case of morphine.

Nabil El Bitar, Bernard Pollin, Elias Karroum, Ivanne Pincedé, Daniel Le Bars

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of neurophysiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Nabil El BitarSorbonne Universités, Université Pierre et Marie Curie, Faculté de Médecine, Paris, France; and.
Bernard PollinSorbonne Universités, Université Pierre et Marie Curie, Faculté de Médecine, Paris, France; and.
Elias KarroumSorbonne Universités, Université Pierre et Marie Curie, Faculté de Médecine, Paris, France; and.
Ivanne PincedéSorbonne Universités, Université Pierre et Marie Curie, Faculté de Médecine, Paris, France; and.
Daniel Le BarsSorbonne Universités, Université Pierre et Marie Curie, Faculté de Médecine, Paris, France; and daniel.le_bars@upmc.fr.
Neurosciences Paris-SeineSorbonne Université · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In thermoneutral conditions, rats display cyclic variations of the vasomotion of the tail and paws, the most widely used target organs in current acute or chronic animal models of pain. Systemic morphine elicits their vasoconstriction followed by hyperthermia in a naloxone-reversible and dose-dependent fashion. The dose-response curves were steep with ED

Indexed as

Action PotentialsAnalgesics, OpioidAnimalsBlood PressureBody Temperature RegulationGABA-A Receptor AgonistsHeart RateMaleMedulla OblongataMidbrain Raphe NucleiModels, BiologicalMorphineMuscimolNaloxoneNarcotic AntagonistsNeuronsAnalgesics, OpioidGABA-A Receptor AgonistsMorphineMuscimolNaloxoneNarcotic Antagonistsblood pressurecore temperatureheart ratemorphineratrostral medullary rapherostral ventromedial medullaskin temperaturethermoregulation

Identifiers

PMID27605533
PMCPMC5133307
OpenAlexW2511745919

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.