Evidence map›Paper›PMID 27605514›Full record

ArticleG3 (Bethesda, Md.)2016

Effect of Two Lipoprotein (a)-Associated Genetic Variants on Plasminogen Levels and Fibrinolysis.

Hong Wang, Chan E Hong, Joshua P Lewis, Yanbei Zhu, Xing Wang, Xin Chu, Joshua Backman, Ziying Hu, Peixin Yang, Christopher D Still and 2 more

Open access · goldAbstract read
In one paragraph

Article in G3 (Bethesda, Md.), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
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  4. Review
  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

Hong WangDivision of Endocrinology, Diabetes, and Nutrition, University of Maryland School of Medicine, Baltimore, Maryland 21201.
Chan E HongDivision of Endocrinology, Diabetes, and Nutrition, University of Maryland School of Medicine, Baltimore, Maryland 21201.
Joshua P LewisDivision of Endocrinology, Diabetes, and Nutrition, University of Maryland School of Medicine, Baltimore, Maryland 21201.
Yanbei ZhuDivision of Endocrinology, Diabetes, and Nutrition, University of Maryland School of Medicine, Baltimore, Maryland 21201.
Xing WangDivision of Endocrinology, Diabetes, and Nutrition, University of Maryland School of Medicine, Baltimore, Maryland 21201.
Xin ChuGeisinger Obesity Institute, Geisinger Clinic, Danville, Pennsylvania 17822.
Joshua BackmanDivision of Endocrinology, Diabetes, and Nutrition, University of Maryland School of Medicine, Baltimore, Maryland 21201.
Ziying HuDivision of Endocrinology, Diabetes, and Nutrition, University of Maryland School of Medicine, Baltimore, Maryland 21201.
Peixin YangDepartment of Obstetrics, Gynecology, & Reproductive Sciences, University of Maryland School of Medicine, Baltimore, Maryland 21201.
Christopher D StillGeisinger Obesity Institute, Geisinger Clinic, Danville, Pennsylvania 17822.
Glenn S GerhardGeisinger Obesity Institute, Geisinger Clinic, Danville, Pennsylvania 17822.
Mao FuDivision of Endocrinology, Diabetes, and Nutrition, University of Maryland School of Medicine, Baltimore, Maryland 21201 mfu@medicine.umaryland.edu.ORCID http://orcid.org/0000-0002-9904-5537
University of Maryland, Baltimore · USDalian Medical University · CNPennsylvania State University · US

Funding

Research BaseP30DK072488 · NIDDK · UNIVERSITY OF MARYLAND BALTIMORE · PI MITCHELL, BRAXTON D, TAYLOR, SIMEON I. · 2005 to 2019
$17.3M
Pharmacogenomics of Anti-platlet Intervention-2 (PAPI-2) StudyU01HL105198 · NHLBI · UNIVERSITY OF MARYLAND BALTIMORE · PI SHULDINER, ALAN R. · 2010 to 2014
$13.6M
Genome-wide Search for CVD Gene-Environment InteractionsU01HL072515 · NHLBI · UNIVERSITY OF MARYLAND BALTIMORE · PI SHULDINER, ALAN R. · 2002 to 2008
$11.2M
Longevity Genes in Founder PopulationsR01AG018728 · NIA · UNIVERSITY OF MARYLAND BALTIMORE · PI SHULDINER, ALAN R. · 2001 to 2005
$3.8M
Genetic Determinants of Weight Loss and Resolution of Co-MorbiditiesR01DK088231 · NIDDK · TEMPLE UNIV OF THE COMMONWEALTH · PI GERHARD, GLENN S · 2011 to 2015
$2.5M
NHLBI NIH HHS U01 HL072515NHLBI NIH HHS U01 HL105198NIA NIH HHS R01 AG018728NIDDK NIH HHS P30 DK072488NIDDK NIH HHS R01 DK088231
6 · The paper itself

Abstract

Two genetic variants (rs3798220 and rs10455872) in the apolipoprotein (a) gene (

Indexed as

fibrinolysisgeneticslipoprotein (a)plasminogenthrombogenicity

Identifiers

PMID27605514
PMCPMC5100851
OpenAlexW2520404284

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.