Analysis of the Effects of Cell Stress and Cytotoxicity on In Vitro Assay Activity Across a Diverse Chemical and Assay Space.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

39 citing papers in PubMed.

1. Maackiain Reduces Neuroinflammation by Modulating Inflammatory Signals in LPS-InducedJournal of microbiology and biotechnology · 2026
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3. Mapping out strategies to further develop human-relevant, new approach methodology (NAM)-based developmental neurotoxicity (DNT) testing.ALTEX · 2025
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4. Pervasive environmental chemicals impair oligodendrocyte development.Nature neuroscience · 2024
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5. Comparison of in silico, in vitro, and in vivo toxicity benchmarks suggests a role for ToxCast data in ecological hazard assessment.Toxicological sciences : an official journal of the Society of Toxicology · 2023
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6. Computational Construction of Toxicant Signaling Networks.Chemical research in toxicology · 2023
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7. Pervasive environmental chemicals impair oligodendrocyte development.bioRxiv : the preprint server for biology · 2023
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8. The ToxCast pipeline: updates to curve-fitting approaches and database structure.Frontiers in toxicology · 2023
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9. Substantiate a read-across hypothesis by using transcriptome data-A case study on volatile diketones.Frontiers in toxicology · 2023
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10. Advances in computational methods along the exposure to toxicological response paradigm.Toxicology and applied pharmacology · 2022
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11. Chemical Mixtures in Household Environments: In Silico Predictions and In Vitro Testing of Potential Joint Action on PPARγ in Human Liver Cells.Toxics · 2022
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12. Accounting for Artifacts in High-Throughput Toxicity Assays.Methods in molecular biology (Clifton, N.J.) · 2022
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13. Computational model for fetal skeletal defects potentially linked to disruption of retinoic acid signaling.Frontiers in pharmacology · 2022
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14. Update and Evaluation of a High-Throughput In Vitro Mass Balance Distribution Model: IV-MBM EQP v2.0.Toxics · 2021
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15. Predictive modeling of biological responses in the rat liver usingComputational toxicology (Amsterdam, Netherlands) · 2021
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16. High-Throughput Transcriptomics Platform for Screening Environmental Chemicals.Toxicological sciences : an official journal of the Society of Toxicology · 2021
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17. The EU-ToxRisk method documentation, data processing and chemical testing pipeline for the regulatory use of new approach methods.Archives of toxicology · 2020
    Article
18. Rapid hazard characterization of environmental chemicals using a compendium of human cell lines from different organsALTEX · 2020
    Article
19. Potential of ToxCast Data in the Safety Assessment of Food Chemicals.Toxicological sciences : an official journal of the Society of Toxicology · 2020
    Article
20. New Approach Methods to Evaluate Health Risks of Air Pollutants: Critical Design Considerations for In Vitro Exposure Testing.International journal of environmental research and public health · 2020
    Review

Corrections and comments

• Erratum for
  Editor's Highlight: Analysis of the Effects of Cell Stress and Cytotoxicity on In Vitro Assay Activity Across a Diverse Chemical and Assay Space.2016

Authors and funding

21 authors.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.